[HTML][HTML] Therapeutic approaches for the treatment of head and neck squamous cell carcinoma–An update on clinical trials
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common non-skin
cancer with a tobacco consumption and infection with high-risk human papillomavirus (HPV) …
cancer with a tobacco consumption and infection with high-risk human papillomavirus (HPV) …
Cancer stem cells in head and neck squamous cell carcinoma: identification, characterization and clinical implications
C Peitzsch, J Nathansen, SI Schniewind, F Schwarz… - Cancers, 2019 - mdpi.com
Head and neck squamous cell carcinoma (HNSCC) is the sixth most commonly diagnosed
cancer worldwide. Despite advances in the treatment management, locally advanced …
cancer worldwide. Despite advances in the treatment management, locally advanced …
Rethink of EGFR in cancer with its kinase independent function on board
R Thomas, Z Weihua - Frontiers in oncology, 2019 - frontiersin.org
The epidermal growth factor receptor (EGFR) is one of most potent oncogenes that are
commonly altered in cancers. As a receptor tyrosine kinase, EGFR's kinase activity has been …
commonly altered in cancers. As a receptor tyrosine kinase, EGFR's kinase activity has been …
[HTML][HTML] Head and neck cancer organoids established by modification of the CTOS method can be used to predict in vivo drug sensitivity
N Tanaka, AA Osman, Y Takahashi, A Lindemann… - Oral oncology, 2018 - Elsevier
Objectives Currently there are no standard biomarkers of head and neck squamous cell
carcinoma (HNSCC) response to therapy. This is, due to a lack of adequate predictive tumor …
carcinoma (HNSCC) response to therapy. This is, due to a lack of adequate predictive tumor …
IFIT1 and IFIT3 promote oral squamous cell carcinoma metastasis and contribute to the anti-tumor effect of gefitinib via enhancing p-EGFR recycling
IFIT1 and IFIT3 are abundant products of interferon-stimulating genes. While the importance
of IFIT1 and IFIT3 in the prognosis of cancer has been reported, the molecular basis of IFIT1 …
of IFIT1 and IFIT3 in the prognosis of cancer has been reported, the molecular basis of IFIT1 …
The story of EGFR: from signaling pathways to a potent anticancer target
S Ramani, S Samant, SM Manohar - Future Medicinal Chemistry, 2022 - Taylor & Francis
EGFR is a member of the ERBB family. It plays a significant role in cellular processes such
as growth, survival and differentiation via the activation of various signaling pathways. EGFR …
as growth, survival and differentiation via the activation of various signaling pathways. EGFR …
Recent insights into the molecular basis of Fanconi anemia: genes, modifiers, and drivers
RS Cheung, T Taniguchi - International journal of hematology, 2017 - Springer
Fanconi anemia (FA), the most common form of inherited bone marrow failure, predisposes
to leukemia and solid tumors. FA is caused by the genetic disruption of a cellular pathway …
to leukemia and solid tumors. FA is caused by the genetic disruption of a cellular pathway …
Dual-color bioluminescent sensor proteins for therapeutic drug monitoring of antitumor antibodies
M van Rosmalen, Y Ni, DFM Vervoort, R Arts… - Analytical …, 2018 - ACS Publications
Monitoring the levels of therapeutic antibodies in individual patients would allow patient-
specific dose optimization, with the potential for major therapeutic and financial benefits. Our …
specific dose optimization, with the potential for major therapeutic and financial benefits. Our …
Nimotuzumab for patients with inoperable cancer of the head and neck
T Crombet Ramos, B Mestre Fernández… - Frontiers in …, 2020 - frontiersin.org
EGFR activation induces cell proliferation, neoformation of blood vessels, survival, and
metastasis of the cancer cells. Nimotuzumab is an engineered, intermediate affinity anti …
metastasis of the cancer cells. Nimotuzumab is an engineered, intermediate affinity anti …
Precision therapy of head and neck squamous cell carcinoma
Precision medicine is an approach to disease prevention and treatment that takes into
account genetic variability and environmental and lifestyle influences that are unique to …
account genetic variability and environmental and lifestyle influences that are unique to …