Skeletal muscle regeneration is a complex process orchestrated by multiple steps. Recent
findings indicate that inflammatory responses could play central roles in bridging initial …

Polymorphonuclear neutrophils, besides their involvement in primary defense against
infections–mainly through phagocytosis, generation of toxic molecules, release of enzymes …

Of all cells implicated in the pathology of rheumatoid arthritis (RA), neutrophils possess the
greatest cytotoxic potential, owing to their ability to release degradative enzymes and …

Cytokines and chemokines are proteins that coordinate the immune response throughout
the body. The dysregulation of cytokines and chemokines is a central feature in the …

Neutrophils have long been viewed as the final effector cells of an acute inflammatory
response, with a primary role in the clearance of extracellular pathogens. However, more …

Neutrophils, the most abundant white blood cells in human circulation, entertain intense
interactions with other leukocyte subsets, platelets, and stromal cells. Molecularly, such …

Chronic inflammation fosters cancer development and progression and also modulates
tumor responses to anticancer therapies. Neutrophils are key effector cells in innate …

Neutrophils are critical cells of the innate immune system and rapidly respond to tissue
injury and infection. Increasing evidence also indicates that neutrophils have versatile …

It is now widely recognized that neutrophils are highly versatile and sophisticated cells that
display de novo synthetic capacity and may greatly extend their lifespan. In addition …

Neutrophils are pivotal effector cells of innate immunity. Their recruitment into peripheral
tissues is indispensable for host defense. Given their destructive potential, neutrophil entry …