Depression is one of the most frequent and burdensome non-motor symptoms in
Parkinson's disease (PD), across all stages. Even when its severity is mild, PD depression …

Normal maintenance of human motivation depends on the integrity of subcortical structures
that link the prefrontal cortex with the limbic system. Structural and functional disruption of …

Sleep disorders are among the most common non-motor manifestations in Parkinson's
disease (PD) and have a significant negative impact on quality of life. While sleep disorders …

Apathy is a frequently reported neuropsychiatric symptom in Parkinson's disease (PD), but
its prevalence and clinical correlates are debated. We aimed to address these issues by …

Depression occurs in around 35% of patients with Parkinson disease (PD) and is often
persistent. Symptoms of depression can be evident in individuals at the time of diagnosis …

A dopaminergic deficiency in patients with Parkinson's disease (PD) causes abnormalities of
movement, behaviour, learning, and emotions. The main motor features (ie, tremor, rigidity …

Stress is critically involved in the development and progression of disease. From the stress
of undergoing treatments to facing your own mortality, the physiological processes that …

Parkinson's disease is a neurodegenerative disorder characterized by motor and nonmotor
symptoms. Psychosis is a common feature of Parkinson's disease. Parkinson's disease …

Objectives The description of minor hallucinatory phenomena (presence, passage
hallucinations) has widened the spectrum of psychosis in Parkinson's disease (PD). Minor …

Objective: Despite the negative effects of depression in Parkinson's disease, there is
currently no evidence-based standard of care. The purpose of this study was to examine the …