Spontaneous preterm birth: Involvement of multiple feto-maternal tissues and organ systems, differing mechanisms, and pathways
MS Vidal Jr, RCV Lintao, MEL Severino… - Frontiers in …, 2022 - frontiersin.org
Survivors of preterm birth struggle with multitudes of disabilities due to improper in utero
programming of various tissues and organ systems contributing to adult-onset diseases at a …
programming of various tissues and organ systems contributing to adult-onset diseases at a …
Fetal inflammatory response at the fetomaternal interface: A requirement for labor at term and preterm
R Menon - Immunological reviews, 2022 - Wiley Online Library
Human parturition at term and preterm is an inflammatory process synchronously executed
by both fetomaternal tissues to transition them from a quiescent state t an active state of …
by both fetomaternal tissues to transition them from a quiescent state t an active state of …
[HTML][HTML] Macrophages exert homeostatic actions in pregnancy to protect against preterm birth and fetal inflammatory injury
N Gomez-Lopez, V Garcia-Flores, PY Chin… - JCI insight, 2021 - ncbi.nlm.nih.gov
Macrophages are commonly thought to contribute to the pathophysiology of preterm labor by
amplifying inflammation—but a protective role has not previously been considered to our …
amplifying inflammation—but a protective role has not previously been considered to our …
A key role for NLRP3 signaling in preterm labor and birth driven by the alarmin S100B
Preterm birth remains the leading cause of neonatal morbidity and mortality worldwide. A
substantial number of spontaneous preterm births occur in the context of sterile intra …
substantial number of spontaneous preterm births occur in the context of sterile intra …
[HTML][HTML] Fetal and maternal NLRP3 signaling is required for preterm labor and birth
Preterm birth is the leading cause of neonatal morbidity and mortality worldwide. One of
every 4 preterm neonates is born to a mother with intra-amniotic inflammation driven by …
every 4 preterm neonates is born to a mother with intra-amniotic inflammation driven by …
[HTML][HTML] Interactions between microbiota and cervical epithelial, immune, and mucus barrier
M Dong, Y Dong, J Bai, H Li, X Ma, B Li… - Frontiers in cellular …, 2023 - frontiersin.org
The female reproductive tract harbours hundreds of bacterial species and produces
numerous metabolites. The uterine cervix is located between the upper and lower parts of …
numerous metabolites. The uterine cervix is located between the upper and lower parts of …
Mueller matrix imaging for collagen scoring in mice model of pregnancy
Preterm birth risk is associated with early softening of the uterine cervix in pregnancy due to
the accelerated remodeling of collagen extracellular matrix. Studies of mice model of …
the accelerated remodeling of collagen extracellular matrix. Studies of mice model of …
Parity and gestational age are associated with vaginal microbiota composition in term and late term pregnancies
K Kervinen, T Holster, S Saqib, S Virtanen… - …, 2022 - thelancet.com
Background Vaginal microbiota and its potential contribution to preterm birth is under
intense research. However, only few studies have investigated the vaginal microbiota in …
intense research. However, only few studies have investigated the vaginal microbiota in …
[HTML][HTML] Modeling ascending Ureaplasma parvum infection through the female reproductive tract using vagina-cervix-decidua-organ-on-a-chip and feto-maternal …
OAG Tantengco, LS Richardson… - … : official publication of …, 2022 - ncbi.nlm.nih.gov
Genital mycoplasmas can break the cervical barrier and cause intraamniotic infection and
preterm birth. This study developed a six-chamber vagina-cervix-decidua-organ-on-a-chip …
preterm birth. This study developed a six-chamber vagina-cervix-decidua-organ-on-a-chip …
Parturition in mammals: Animal models, pain and distress
J Martínez-Burnes, R Muns, H Barrios-García… - Animals, 2021 - mdpi.com
Simple Summary Labour is considered a painful episode where complex physiological,
hormonal, morphological, and behavioural changes are present. During animal parturition …
hormonal, morphological, and behavioural changes are present. During animal parturition …