Lactoferrin (LF) is a multifunctional iron-binding glycoprotein that exhibits a variety of
properties, such as immunomodulatory, anti-inflammatory, antimicrobial, and anticancer, that …

Pseudomonas aeruginosa is a highly adaptable opportunistic pathogen capable of
exploiting barriers and immune defects to cause chronic lung infections in conditions such …

Background While the widespread initiation of elexacaftor/tezacaftor/ivacaftor (ETI) has led
to dramatic clinical improvements among persons with cystic fibrosis (pwCF), little is known …

Introduction While cystic fibrosis (CF) lung disease is characterized by persistent
inflammation and infections and chronic inflammatory diseases are often accompanied by …

Nearly one-half of patients with cystic fibrosis (CF) carry the homozygous F508del mutation
in the cystic fibrosis transmembrane conductance regulator (CFTR) gene but exhibit variable …

Cystic fibrosis (CF) is a rare genetic disease caused by genetic variants of the cystic fibrosis
transmembrane conductance regulator (CFTR)[1]. This disease is characterized by microbial …

IgE antibodies against the allergen Ara-h2 can cause life-threatening anaphylaxis upon
exposure to peanuts. Desensitization strategies aim at inducing IgG responses against Ara …

The pseudohypohalous acid hypothiocyanite/hypothiocyanous acid (OSCN−/HOSCN) has
been known to play an antimicrobial role in mammalian immunity for decades. It is a potent …

Background The pathogenesis and clinical diagnosis of lung adenocarcinoma (LUAD), a
malignant illness with substantial morbidity and mortality, are still being investigated. Genes …

Cystic fibrosis (CF) airway disease is marked by significant regional heterogeneity and
severe neutrophil-predominant inflammation with high levels of proinflammatory cytokines …