Gefitinib and afatinib show potential efficacy for Fanconi anemia–related head and neck cancer
H Montanuy, Á Martínez-Barriocanal… - Clinical Cancer …, 2020 - AACR
Purpose: Fanconi anemia rare disease is characterized by bone marrow failure and a high
predisposition to solid tumors, especially head and neck squamous cell carcinoma …
predisposition to solid tumors, especially head and neck squamous cell carcinoma …
Constructing a passive targeting and long retention therapeutic nanoplatform based on water-soluble, non-toxic and highly-stable core–shell poly (amino acid) …
X Wang, B Deng, M Yu, T Zeng, Y Chen, J Hu… - Biomaterials …, 2021 - pubs.rsc.org
Drug delivery nanoplatforms have been applied in bioimaging, medical diagnosis, drug
delivery and medical therapy. However, insolubility, toxicity, instability, nonspecific targeting …
delivery and medical therapy. However, insolubility, toxicity, instability, nonspecific targeting …
Mertk inhibition: potential as a treatment strategy in egfr tyrosine kinase inhibitor-resistant non-small cell lung cancer
CJ Chen, YP Liu - Pharmaceuticals, 2021 - mdpi.com
Epidermal growth factor tyrosine kinase inhibitors (EGFR-TKIs) are currently the most
effective treatment for non-small cell lung cancer (NSCLC) patients, who carry primary EGFR …
effective treatment for non-small cell lung cancer (NSCLC) patients, who carry primary EGFR …
Molecular Analysis of ZNF71 KRAB in Non-Small-Cell Lung Cancer
Our previous study found that zinc finger protein 71 (ZNF71) mRNA expression was
associated with chemosensitivity and its protein expression was prognostic of non-small-cell …
associated with chemosensitivity and its protein expression was prognostic of non-small-cell …
Mechanism of hepatotoxicity of first-line tyrosine kinase inhibitors: Gefitinib and afatinib
Y Zhang, Y Cai, SR Zhang, CY Li, LL Jiang, P Wei… - Toxicology Letters, 2021 - Elsevier
Aims Both gefitinib and afatinib are epidermal growth factor tyrosine kinase inhibitors (EGFR-
TKI) in the treatment of non-small cell lung cancer (NSCLC). It has been reported that …
TKI) in the treatment of non-small cell lung cancer (NSCLC). It has been reported that …
Identification of prognostic and chemopredictive microRNAs for non-small-cell lung cancer by integrating SEER-medicare data
Q Ye, J Putila, R Raese, C Dong, Y Qian… - International Journal of …, 2021 - mdpi.com
This study developed a novel methodology to correlate genome-scale microRNA (miRNA)
expression profiles in a lung squamous cell carcinoma (LUSC) cohort (n= 57) with …
expression profiles in a lung squamous cell carcinoma (LUSC) cohort (n= 57) with …
Prediction of co-amorphous formation using non-bonded interaction energy: Molecular dynamic simulation and experimental validation
Y Deng, W Luo, Z Zheng, G Wei, S Liu, Y Jiang… - Chemical Engineering …, 2023 - Elsevier
Co-amorphous (CA) formulation is a promising strategy to improve the solubility of poorly
water-soluble drugs, however, effective prediction of a CA system is a challenge. In this …
water-soluble drugs, however, effective prediction of a CA system is a challenge. In this …
Update review of skin adverse events during treatment of lung cancer and colorectal carcinoma with epidermal growth receptor factor inhibitors
Y Peng, Q Li, J Zhang, W Shen, X Zhang, C Sun… - BioScience …, 2018 - jstage.jst.go.jp
The past decades have witnessed a rapid increase in the use of molecularly targeted
therapies. One class of agents includes the epidermal growth factor receptor inhibitors …
therapies. One class of agents includes the epidermal growth factor receptor inhibitors …
[HTML][HTML] Real-world clinical outcomes of first-generation and second-generation epidermal growth factor receptor tyrosine kinase inhibitors in a large cohort of …
A Pluzanski, M Krzakowski, D Kowalski… - ESMO open, 2020 - Elsevier
Background First-generation or second-generation epidermal growth factor receptor (EGFR)
tyrosine kinase inhibitors (TKIs) are commonly used in EGFR-mutation-positive advanced …
tyrosine kinase inhibitors (TKIs) are commonly used in EGFR-mutation-positive advanced …
Fungal antitumor protein D1 is internalized via endocytosis and inhibits non-small cell lung cancer proliferation through MAPK signaling pathway
MH Zhang, JH Wong, F Liu, TB Ng, ZK Liu - International Journal of …, 2023 - Elsevier
Lung cancer has the highest mortality among cancer-related deaths worldwide. Among lung
cancers, non-small cell lung cancer (NSCLC) is the most common histological type. In the …
cancers, non-small cell lung cancer (NSCLC) is the most common histological type. In the …