Versatile strategies have been developed to construct electrospun fiber-based drug delivery
systems for tissue regeneration and cancer therapy. We first introduce the construction of …

The successful transplantation of stem cells has the potential to transform regenerative
medicine approaches and open promising avenues to repair, replace, and regenerate …

Oxidative stress (OS) plays a critical role in the pathophysiology of several brain-related
disorders, including neurodegenerative diseases and ischemic stroke, which are the major …

Ischemic stroke is a challenging disease with high mortality and disability rates, causing a
great economic and social burden worldwide. During ischemic stroke, ionic imbalance and …

Stroke is the leading neurological cause of death and disability all over the world, with few
effective drugs. Nerve growth factor (NGF) is well known for its multifaceted neuroprotective …

A variety of neuroprotectants have shown promise in treating ischemic stroke, yet their
delivery to the brain remains a challenge. The endothelial cells lining the blood-brain barrier …

Neurological and functional recovery is limited following central nervous system injury and
severe injury to the peripheral nervous system. Extracellular matrix (ECM)‐mimetic …

Exosomes are natural cells-derived vesicles, which are at the forefront toward clinical
success for various diseases, including cerebral ischemia. Exosomes mediate cell-to-cell …

In a subset of patients, chronic exposure to stress is an etiological risk factor for
neuroinflammation and depression. Neuroinflammation affects up to 27% of patients with …

Traumatic brain injury (TBI) is one of the most devastating nervous injuries. Neural tissue
engineering based on stem cells and bioactive scaffold is a promising but challenging …