The epidemiological studies have indicated a possible oncostatic property of melatonin on
different types of tumors. Besides, experimental studies have documented that melatonin …

IgG4-related disease is a newly recognized fibro-inflammatory condition characterized by
several features: a tendency to form tumefactive lesions in multiple sites; a characteristic …

Survival data for pancreatic cancer are usually based on actuarial calculations and actual
long-term survival rates are rarely reported. Here we use population-level data from the …

Conventional methods for histopathologic tissue diagnosis are labor-and time-intensive and
can delay decision-making during diagnostic and therapeutic procedures. We report the …

Sonic hedgehog (Shh), a soluble ligand overexpressed by neoplastic cells in pancreatic
ductal adenocarcinoma (PDAC), drives formation of a fibroblast-rich desmoplastic stroma …

Tissue diagnosis is important during surgical excision of solid tumors for margin evaluation.
Conventional histopathologic methods rely heavily on image-based visual diagnosis by …

Introduction Actual 5-year survival rates of 10–18% have been reported for patients with
resected pancreatic adenocarcinoma (PC), but the use of multimodality therapy was …

Objective: To determine long-term survival after pancreatoduodenectomy for pancreatic
ductal adenocarcinoma and to identify clinical factors associated with long-term survival …

Pancreatic cancer cells intimately interact with a complex microenvironment that influences
pancreatic cancer progression. The pancreas is innervated by fibers of the sympathetic …

Pancreatic cancer continues to pose an enormous challenge to clinicians and cancer
scientists. With a more affluent world the global incidence of pancreatic cancer is rising. For …