Despite declining incidence and mortality rates in many countries, the abdominal aortic
aneurysm (AAA) continues to represent a life-threatening cardiovascular condition with an …

Aortic disease has many forms including aortic aneurysm and dissection, aortic coarctation
or abnormalities in aortic function, such as loss of aortic distensibility. Genetic analysis in …

Rationale Aortic aneurysm (AA) is a serious condition that largely increases the risk of aortic
dissection and sudden death. Exploring the global burden of disease and changes in risk …

Inflammation and activation of the immune system are key molecular and cellular events in
the pathogenesis of cardiovascular diseases, including atherosclerosis, hypertension …

Abdominal aortic aneurysm (AAA) is a degenerative vascular disease with a complex
aetiology that remains to be fully elucidated. Clinical management of AAA is limited to …

Background Angiotensin II type 1 receptor blockers (ARBs) have been shown to limit the
growth of abdominal aortic aneurysm (AAA), but their efficacy is controversial. This study …

Objective Abdominal aortic aneurysm (AAA) is a common progressive disease and a
significant cause of morbidity and mortality. Prior investigations have shown that diabetes …

The effects of the selective AT2R (angiotensin AT2 receptor) agonist, Compound 21 (C21),
on abdominal aortic aneurysm formation were investigated in normotensive Wistar rats …

Abdominal aortic aneurysm (AAA) is a progressive disease that has an increasing
prevalence with aging, but no effective pharmacological therapy to attenuate AAA …

Aortic pathologies such as aneurysm, dissection and trauma are relatively common and
potentially fatal diseases. Over the past two decades, we have experienced unprecedented …