Astaxanthin: A mechanistic review on its biological activities and health benefits

S Fakhri, F Abbaszadeh, L Dargahi, M Jorjani - Pharmacological research, 2018 - Elsevier
Astaxanthin (AST) is a potent lipid-soluble keto-carotenoid with auspicious effects on human
health. It protects organisms against a wide range of diseases with excellent safety and …

Bioactivities of astaxanthin from natural sources, augmenting its biomedical potential: A review

PA Aneesh, KK Ajeeshkumar, RGK Lekshmi… - Trends in Food Science …, 2022 - Elsevier
Background The wide range of health benefits and variety of biological activities of
carotenoids have made them the focal point of industrial as well as academic research on a …

Dietary astaxanthin: an excellent carotenoid with multiple health benefits

Y Cao, L Yang, X Qiao, C Xue, J Xu - Critical Reviews in Food …, 2023 - Taylor & Francis
Astaxanthin is a carotenoid widely found in marine organisms and microorganisms. With
extensive use in nutraceuticals, cosmetics, and animal feed, astaxanthin will have the …

Therapeutic potential of astaxanthin and superoxide dismutase in Alzheimer's disease

V Balendra, SK Singh - Open biology, 2021 - royalsocietypublishing.org
Oxidative stress, the imbalance of the antioxidant system, results in an accumulation of
neurotoxic proteins in Alzheimer's disease (AD). The antioxidant system is composed of …

[HTML][HTML] The neuroprotective effects of astaxanthin: therapeutic targets and clinical perspective

S Fakhri, I Yosifova Aneva, MH Farzaei… - Molecules, 2019 - mdpi.com
As the leading causes of human disability and mortality, neurological diseases affect
millions of people worldwide and are on the rise. Although the general roles of several …

[HTML][HTML] Molecular mechanisms of astaxanthin as a potential neurotherapeutic agent

EI Bahbah, S Ghozy, MS Attia, A Negida, TB Emran… - Marine drugs, 2021 - mdpi.com
Neurological disorders are diseases of the central and peripheral nervous system that affect
millions of people, and the numbers are rising gradually. In the pathogenesis of …

In vitro studies of the neuroprotective activities of astaxanthin and fucoxanthin against amyloid beta (Aβ1-42) toxicity and aggregation

M Alghazwi, S Smid, I Musgrave, W Zhang - Neurochemistry international, 2019 - Elsevier
Amyloid beta (Aβ) can aggregate and form plaques, which are considered as one of the
major hallmarks of Alzheimer's disease. This study aims to directly compare the …

Thermal stability and oral absorbability of astaxanthin esters from Haematococcus pluvialis in Balb/c mice

Q Zhou, J Xu, L Yang, C Gu… - … of the Science of Food and …, 2019 - Wiley Online Library
BACKGROUND Astaxanthin is used as a functional nutraceutical and pigment in many food
products. It is mostly exists in the form of a fatty acid ester in nature. However, no detailed …

Effects of astaxanthin on sensory‐motor function in a compression model of spinal cord injury: involvement of ERK and AKT signalling pathway

S Fakhri, L Dargahi, F Abbaszadeh… - European Journal of …, 2019 - Wiley Online Library
Background Spinal cord injury (SCI) causes continuous neurological deficits and major
sensory‐motor impairments. There is no effective treatment to enhance sensory‐motor …

Astaxanthin reduces MMP expressions, suppresses cancer cell migrations, and triggers apoptotic caspases of in vitro and in vivo models in melanoma

YT Chen, CJ Kao, HY Huang, SY Huang… - Journal of Functional …, 2017 - Elsevier
This study assessed the use of astaxanthin as an anticancer agent for increasing inhibition
to melanoma cells (A375 and A2058). Wound healing and invasion assays presented that …