CD4 and CD8 molecules are co-receptors of T cell receptors which interact specifically with
MHC class II and I, respectively, during antigen presentation. Here we investigated CD4 and …

Peripheral T-cell lymphoma, not otherwise specified is a heterogeneous group of aggressive
neoplasms with indistinct borders. By gene expression profiling we previously reported …

B-cell receptor (BCR) signals promote survival of chronic lymphocytic leukemia (CLL) cells,
and it is believed that overexpressed and constitutively active Lyn mediates this signaling …

Residual feed intake (RFI) is a measure of feed efficiency, in which low RFI denotes
improved feed efficiency. Caloric restriction (CR) is associated with feed efficiency in …

Nef, an accessory protein of the Human Immunodeficiency Virus type 1 (HIV-1), is
dispensable for viral replication in cell culture, but promotes virus replication and …

Cytotoxic T lymphocytes (CTLs) kill targets by releasing cytotoxic agents from lytic granules.
Killing is a multi‐step process. The CTL adheres to a target, allowing its T‐cell receptors to …

The exact etiology of Parkinson's disease (PD) remains obscure, although many cellular
mechanisms including α-synuclein aggregation, oxidative damage, excessive …

Understanding the broad variety of functions encoded in cellular membranes requires
experimental systems mimicking both their biochemical composition and biophysical …

CD4+ T lymphocytes play crucial roles in the adaptive immune system. CD4, as the most
effective marker to delineate the T-helper subsets, was identified in many fish species. Two …

The generation of phagocytic cups and immunological synapses are crucial events of the
innate and adaptive immune responses, respectively. They are triggered by distinct immune …