Aim: Cytochrome P450s (CYP450) enzymes regulate inflammation and atherosclerosis and
can affect carotid plaque stability in patients with ischemic stroke (IS). This study aimed to …

Aim: To evaluate the relationship between CYP genetic polymorphisms and CYP metabolite
levels with carotid artery stenosis in acute ischemic stroke (IS) patients. Methods: Eleven …

Aim: Ischemic stroke (IS) is a multifactorial disease caused by environmental risk factors and
genetic susceptibility. However, few studies have assessed whether gene–gene interactions …

Aims: To investigate the association of four variants of two CYP ω-hydroxylase genes and 20-
hydroxyeicosatetraenoic acid (HETE) levels with ischemic stroke (IS) and whether gene …

Aims Ischemic stroke (IS) is a multifactorial disease caused by a combination of
environmental risk factors and genetic susceptibilities. However, few studies have assessed …

Background Ischemic stroke (IS) is a leading cause of death and disability worldwide. As
genetic heritability for IS is estimated at about 35%-40%, the identification of genetic variants …

Objective: The present study aims to investigate the relationship between CYP2J2 gene
polymorphisms and ischemic stroke (IS) in a Chinese Han population. Methods: We …

To evaluate the associations between four single-nucleotide polymorphisms (SNPs) in
CYP4A11 and CYP4F2 and ischemic stroke (IS), and between these variants and …

Background The contributions of gene–gene interactions to pathogenesis of stroke remain
largely elusive. The present study was designed to investigate the associations between …

目的探讨花生四烯酸(AA) 细胞色素P450 酶(CYP) 代谢通路基因多态性及基因-
基因交互作用与脑梗死发病的相关性. 方法选择经头颅CT 和/或MRI 检查确诊, 起病72h 内入院 …