Nowadays, obesity is seriously increasing in most of the populations all over the world, and
is associated with the development and progression of high-mortality diseases such as type …

It has been more than three decades since peroxisome proliferator-activated receptors
(PPARs) were first discovered. Many investigations have revealed the central regulators of …

Cold-induced thermogenesis is an energy-demanding process that protects endotherms
against a reduction in ambient temperature. Using non-targeted liquid chromatography …

The present study was designed to investigate the effects of cold on brown adipose tissue
(BAT) energy substrate utilization in vivo using the positron emission tomography tracers …

Monitoring subcellular functional and structural changes associated with metabolism is
essential for understanding healthy tissue development and the progression of numerous …

Atherosclerosis, for which hyperlipidemia is a major risk factor, is the leading cause of
morbidity and mortality in Western society, and new therapeutic strategies are highly …

Brown adipose tissue (BAT) produces heat by burning TGs that are stored within
intracellular lipid droplets and need to be replenished by the uptake of TG-derived FA from …

In rodents, brown adipose tissue (BAT) plays an important role in producing heat to defend
against the cold and can metabolize large amounts of dietary fatty acids (DFA). The role of …

Metformin is the first-line drug for the treatment of type 2 diabetes. Besides its well-
characterized antihyperglycemic properties, metformin also lowers plasma VLDL triglyceride …

Obesity has reached epidemic proportions, leading to severe associated pathologies such
as insulin resistance, cardiovascular disease, cancer and type 2 diabetes. Adipose tissue …