Acute respiratory distress syndrome (ARDS) is a severe pulmonary reaction requiring
hospitalization, which is incited by many causes, including bacterial and viral pneumonia as …

The recent coronavirus disease-2019 (COVID-19) outbreak has increased at an alarming
rate, representing a substantial cause of mortality worldwide. Respiratory injuries are major …

Acute lung injury (ALI) is well defined in humans, but there is no agreement as to the main
features of acute lung injury in animal models. A Committee was organized to determine the …

Rationale: Experimental data suggest that manipulation of alveolar fluid clearance with β-
agonists can accelerate the resolution of alveolar edema and improve survival. Objective: To …

Background Highly pathogenic avian influenza viruses can cause severe forms of acute
lung injury (ALI) in humans, where pulmonary flooding leads to respiratory failure. The …

Robust and reproducible in vitro models are required for investigating the pathways involved
in fluid homeostasis in the human alveolar epithelium. We performed functional and …

The unique characteristics of pulmonary circulation and alveolar-epithelial capillary-
endothelial barrier allow for maintenance of the air-filled, fluid-free status of the alveoli …

Background and objective Acute respiratory distress syndrome (ARDS) has a high mortality
rate of 35–46% depending on its severity. Animal models are crucial to better understand …

Abstract Resolvin D1 (7S, 8R, 17S-trihydroxy-4Z, 9E, 11E, 13Z, 15E, 19Z-docosahexaenoic
acid)(RvD1), generated from ω-3 fatty docosahexaenoic acids, is believed to exert anti …

Background Histone deacetylase (HDAC) inhibitors, developed as promising anti-tumor
drugs, exhibit their anti-inflammatory properties due to their effects on reduction of …