New benzodioxole-based pyrazoline derivatives: Synthesis and anticandidal, in silico ADME, molecular docking studies

A Özdemir, B Sever, MD Altıntop - Letters in Drug Design & …, 2019 - ingentaconnect.com
Background: Azoles are commonly used in the treatment and prevention of fungal infections.
They suppress fungal growth by acting on the heme group of lanosterol 14α-demethylase …

Synthesis of new thiazolyl-pyrazoline derivatives and evaluation of their antimicrobial, cytotoxic and genotoxic effects

B Sever, MD Altıntop, HK Gencer… - Letters in Drug …, 2018 - ingentaconnect.com
Background: Pyrazolines have played a pivotal role in antimicrobial and anticancer drug
discovery. Moreover, thiazoles have attracted a great deal of interest due to their crucial …

Microwave-Assisted Stereoselective Heterocyclization to Novel Ring d-fused Arylpyrazolines in the Estrone Series

G Mótyán, B Molnár, J Wölfling, É Frank - Molecules, 2019 - mdpi.com
Microwave-assisted syntheses of novel ring d-condensed 2-pyrazolines in the estrone
series were efficiently carried out from steroidal α, β-enones and hydrazine derivatives. The …

Synthetic Strategies of Pyrazoline Derivatives for the Development of New Anticancer Agents: Recent Updates

PK Ray, A Mazumder, R Kumar… - Mini-Reviews in …, 2024 - ingentaconnect.com
Background: Pyrazoline is a heterocyclic compound with five members, two nitrogen atoms
in a circle, and one endocyclic bond. Pyrazoline is a popular electron-rich nitrogen carrier …

Synthesis of some new 2-substituted-4-sulfamoylphenylazo-thiophene and/or thiazole derivatives as antibacterial agents

AA Fadda, AM El-badraw, HM Refat… - … , Sulfur, and Silicon and …, 2016 - Taylor & Francis
Benzoylacetone has been reacted with phenyl isothiocyanate to afford two different
thiocarbamoyl derivatives (α-phenylthiocarbamoyl benzoylacetone and benzoyl …

Fighting Against Alzheimer's Disease: Synthesis of New Pyrazoline and Benzothiazole Derivatives as New Acetylcholinesterase and MAO Inhibitors

G Turan-Zitouni, W Hussein, BN Saglik… - Letters in Drug …, 2018 - ingentaconnect.com
Background: Alzheimer's Disease (AD) is a complicated neurodegenerative disorder with a
multifaceted pathogenesis. AD, characterized by gradual memory loss, falling in language …

[PDF][PDF] Chalconoid derived heterocycles as potent bioactive molecules: A review

S Sapra, K Sharma, Y Bhalla, KL Dhar - Chem. Sci. J, 2016 - academia.edu
Chemical Sciences Journal Page 1 Volume 7 • Issue 2 • 1000129 Chem Sci J ISSN: 2150-3494
CSJ, an open access journal Research Article Open Access Sapra et al., Chem Sci J 2016 …

Utility involving thioacetoacetanilides as precursors for synthesis of new thiazole, thiadiazole and thiophene derivatives with antimicrobial activity

A Fekri, EM Keshk - Journal of Sulfur Chemistry, 2016 - Taylor & Francis
The behavior of thioacetoacetanilide (1) and/or α-arylhydrazono-thioacetoacetanilides 4
toward many different α-halocarbonyl compounds was demonstrated. Thus, reactions of 1 …

Thiophene-based N-phenyl pyrazolines: Synthesis, anticancer activity, molecular docking and ADME study

I Chunaifah, RE Venilita, PJP Tjitda, E Astuti… - Journal of Applied …, 2024 - japsonline.com
This investigation aimed to synthesize and evaluate the anticancer potential of thiophene-
based N-phenyl pyrazoline derivatives containing methoxy groups using both in vitro and in …

[PDF][PDF] Synthesis and structural characterization of novel 2-pyrazoline derivatives: evaluation of their antiproliferative activity and fluorescence properties

Z Ugras, F Tok, E Salva, G Ultav… - Acta Poloniae …, 2022 - academia.edu
In this study, a series of novel 2-pyrazoline derivatives were synthesized and their structures
were established by using spectral methods. The antiproliferative activities of compounds …