An enzymatic hydrolysate of sardine protein (sardine peptide, SP) derived from sardine
muscle possesses angiotensin I-converting enzyme (ACE) inhibitory activity. In the present …

New onset diabetes (NOD) is common among hypertensive patients, whether they are being
treated for hypertension or not, and is associated with subsequently increased …

Purpose Evidence regarding combination therapy for the management of hypertension is
reviewed. Summary Numerous clinical trials have demonstrated the importance of early …

Insulin resistance, diabetes mellitus, and hypertension are associated with significant
cardiovascula: morbidity and mortality. Lifestyle modifications effectively decrease the risk of …

The present study was designed to investigate the potential of telmisartan, an angiotensin
AT1 receptor, in chronic constriction injury-induced neuropathic pain in rats. Four loose …

Aliment Pharmacol Ther 2011; 34: 840–852 Summary Background In addition to the
circulating (endocrine) renin–angiotensin system (RAS), local renin–angiotensin systems …

Introduction. Aliskiren is the first in a new class of direct renin inhibitors to be approved for
the treatment of hypertension. Patients and methods. In this double-blind, multicentre trial …

As shown in a large clinical prospective trial, inhibition of the renin‐angiotensin system
(RAS) can delay the onset of type 2 diabetes in high‐risk individuals. We evaluated the …

Despite significant growth in the number of drug classes and individual agents available to
combat various cardiovascular (CV) risk factors in clinical practice, the prevalence of these …

BACKGROUND: Angiotensin receptor blockers (ARBs) have been linked to reduced risk of
new-onset diabetes, but the evidence was insufficient. OBJECTIVE AND METHODS: The …