Encapsulation of cargoes in nanocontainers is widely used in different fields to solve the
problems of their solubility, homogeneity, stability, protection from unwanted chemical and …

Recently, two oral-administered peptide pharmaceuticals, semaglutide and octreotide, have
been developed and are considered as a breakthrough in peptide and protein drug delivery …

A novel delivery system based on linolenic acid (LA) conjugated chitosan (CS) polymeric
micelles were proposed for improving the oral absorption of doxorubicin (DOX) through …

Our research aimed to enhance the oral bioavailability of doxorubicin hydrochloride (DOX·
HCl) while minimizing the potential for myocardial toxicity. To achieve this goal, we …

Glioblastoma multiforme (GBM) is a central nervous system disease with poor prognosis.
Curative treatments for GBM involve chemotherapy, radiotherapy, and surgical pathways …

Background Oral delivery of macromolecules has been limited mainly by their low intestinal
permeability. Chemical permeation enhancers (CPEs) are typically used to improve …

Background Despite the effectiveness of glucagon-like peptide-1 agonist (GLP-1A) in the
treatment of diabetes, its large molecular weight and high hydrophilicity result in poor …

The solubility of rivaroxaban in different solvent mixtures consisting of dichloromethane and
primary alcohols, including methanol, ethanol, n-propanol, and n-butanol, was evaluated …

The increasing worldwide cancer prevalence is a result of population aging and expansion
and changes in individuals' exposure to risk factors, many of which are linked to …

Atorvastatin (ATV) has attracted considerable attention as a potential therapeutic agent for
cancer because it inhibits cancer cell proliferation by suppressing the mevalonate pathway …