Kruppel like factor 2 (KLF2) is a mechanosensitive transcription factor participating in the
regulation of vascular endothelial cells metabolism. Activating KLF2 in endothelial cells …

Substance P (SP) is a tachykinin expressed by various cells in the nervous and immune
systems. SP is predominantly released by neurons and exerts its biological and …

Fatty infiltration, the ectopic deposition of adipose tissue within skeletal muscle, is mediated
via the adipogenic differentiation of fibro-adipogenic progenitors (FAPs). We used single …

Peptide hormones are attractive as injectable therapeutics and imaging agents, but they
often require extensive modification by mutagenesis and/or chemical synthesis to prevent …

Blood vessels and nerves travel together to supply most tissues in the body. However, there
is a knowledge gap in the mechanisms underlying the direct regulation of angiogenesis by …

This review examines the role of the neuropeptide substance P within the
neuroinflammation that follows traumatic brain injury. It examines it in reference to its …

Breast cancer is the second leading cause of cancer death in women with increasing
incidence. Hence, finding a diagnostic factor and/or potential drug target could lead to an …

Substance P is a neuropeptide made up of 11 amino acids—an undecapeptide—and is a
part of the tachykinin neuropeptide family. Its receptor, neurokinin type 1 (NK-1R), is a …

The antinociceptive action of botulinum toxin type A (BoNT/A) has been demonstrated in
behavioral animal studies and clinical settings. It was shown that this effect is associated …

Background Aspiration pneumonia is a serious problem among elderly patients; it is caused
by many risk factors including dysphagia, poor oral hygiene, malnutrition, and sedative …