Postpartum depression (PPD) seriously impairs the physical and mental health of mothers
and their offspring, so how to prevent the occurrence of PPD has essential significance …

Abstract Ethnopharmacological relevance Radix Astragali, a versatile traditional Chinese
medicinal herb, has a rich history dating back to “Sheng Nong's herbal classic”. It has been …

Background Mitochondrial dysfunction leading to disturbances in energy metabolism has
emerged as one of the risk factors in the pathogenesis of depression. Numerous studies …

Depression and Alzheimer's disease (AD) are prevalent neuropsychiatric disorders with
intriguing epidemiological overlaps. Their interrelation has recently garnered widespread …

Post-stroke depression (PSD) is a significant complication in stroke patients, increases long-
term mortality, and exaggerates ischemia-induced brain injury. However, the underlying …

Background Anti-inflammatory agents have emerged as a potential new therapy for major
depressive disorder (MDD). In this meta-analysis, our aim was to evaluate the …

Microglial polarization and associated inflammatory activity are the key mediators of
depression pathogenesis. The natural Smilax glabra rhizomilax derivative engeletin has …

Mounting evidence has identified the rapid and sustained antidepressive and anxiolytic-like
effects of esketamine. However, the underlying mechanism of this no-monoamine target …

Background Lifestyles in children and adolescents are associated with mental health, yet the
combined effects of diet-related joint lifestyles on depression are unclear. Methods A cross …

Introduction Deep brain stimulation (DBS) is an emerging therapy for mood disorders,
particularly treatment-resistant depression (TRD). Different brain areas implicated in …