Arginine Methylation of β-Catenin Induced by PRMT2 Aggravates LPS-Induced Cognitive Dysfunction and Depression-Like Behaviors by Promoting Ferroptosis
L Mao, J You, M Xie, Y Hu, Q Zhou - Molecular Neurobiology, 2024 - Springer
Depression is a prevalent and debilitating psychiatric disorder, imposing substantial societal
and individual burdens. This study aims to investigate the involvement of ferroptosis and …
and individual burdens. This study aims to investigate the involvement of ferroptosis and …
[HTML][HTML] The Therapeutic Effects of Saikosaponins on Depression through the Modulation of Neuroplasticity: From Molecular Mechanisms to Potential Clinical …
S Chen, K Wang, H Wang, Y Gao, K Nie, X Jiang… - Pharmacological …, 2024 - Elsevier
Depression is a major global health issue that urgently requires innovative and precise
treatment options. In this context, saikosaponin has emerged as a promising candidate …
treatment options. In this context, saikosaponin has emerged as a promising candidate …
Explainable depression detection using large language models on social media data
Due to the rapid growth of user interaction on different social media platforms, publicly
available social media data has increased substantially. The sheer amount of data and level …
available social media data has increased substantially. The sheer amount of data and level …
Delivery of bright light therapy within the Veterans Health Administration
DJ Reis, AL Schneider, SE King, JE Forster… - Journal of Affective …, 2024 - Elsevier
Background Bright light therapy (BLT) is efficacious for seasonal and non-seasonal
depression. However, the current state of BLT use in practice is unknown, impeding efforts to …
depression. However, the current state of BLT use in practice is unknown, impeding efforts to …
Depression and risk of infectious diseases: A mendelian randomization study
L Shi, J Ren, K Jin, J Li - Translational Psychiatry, 2024 - nature.com
Previous observational inquiries have revealed a correlation between depression and
infectious maladies. This study seeks to elucidate the causal linkages between depression …
infectious maladies. This study seeks to elucidate the causal linkages between depression …
Impairment in acquisition of conditioned fear in people with depressive symptoms
RH Luo, F Su, XY Zhao, TH Cao, J Liao… - Frontiers in …, 2024 - frontiersin.org
Background Depression is one of the primary global public health issues, and there has
been a dramatic increase in depression levels among young people over the past decade …
been a dramatic increase in depression levels among young people over the past decade …
[HTML][HTML] Gastrodin ameliorates depressive-like behaviors via modulating gut microbiota in CUMS-induced mice
Y Zhao, S Qin, Z Yang, Y Lu, Z Ma, X Ping… - Behavioural Brain …, 2024 - Elsevier
Purpose Depression is a psychiatric disorder and the treatment of depression is an urgent
problem that need to be solved. Gastrodin (GAS) is a Traditional Chinese Medicine from an …
problem that need to be solved. Gastrodin (GAS) is a Traditional Chinese Medicine from an …
Metabolomics in Depression: What We Learn from Preclinical and Clinical Evidences
P Singh, B Vasundhara, N Das, R Sharma… - Molecular …, 2024 - Springer
Depression is one of the predominant common mental illnesses that affects millions of
people of all ages worldwide. Random mood changes, loss of interest in routine activities …
people of all ages worldwide. Random mood changes, loss of interest in routine activities …
[HTML][HTML] ER stress in mouse serotonin neurons triggers a depressive phenotype alleviated by ketamine targeting eIF2α signaling
L Miquel-Rio, U Sarriés-Serrano, M Sancho-Alonso… - Iscience, 2024 - cell.com
Depression is a devastating mood disorder that causes significant disability worldwide.
Current knowledge of its pathophysiology remains modest and clear biological markers are …
Current knowledge of its pathophysiology remains modest and clear biological markers are …
Antidepressant effects of Parishin C in chronic social defeat stress-induced depressive mice
N Jiang, C Yao, Y Zhang, Y Chen, F Chen… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacology relevance Parishin C (Par), a prominent bioactive compound
in Gastrodia elata Blume with little toxicity and shown neuroprotective effects. However, its …
in Gastrodia elata Blume with little toxicity and shown neuroprotective effects. However, its …