Pathogenic role of fibrinogen in the neuropathology of multiple sclerosis: a tale of sorrows and fears
M Alruwaili, HM Al-Kuraishy, A Alexiou… - Neurochemical …, 2023 - Springer
Multiple sclerosis (MS) is an autoimmune demyelinating neurodegenerative disease of the
central nervous system (CNS) due to injury of the myelin sheath by immune cells. The …
central nervous system (CNS) due to injury of the myelin sheath by immune cells. The …
Glial cells: an important switch for the vascular function of the central nervous system
L Gao, X Pan, JH Zhang, Y Xia - Frontiers in Cellular Neuroscience, 2023 - frontiersin.org
In this review, we first describe the current understanding of glial-mediated vascular function
affecting the role of the blood-brain barrier (BBB) in central nervous system (CNS) disorders …
affecting the role of the blood-brain barrier (BBB) in central nervous system (CNS) disorders …
Interrogation of endothelial and mural cells in brain metastasis reveals key immune-regulatory mechanisms
L Bejarano, A Kauzlaric, E Lamprou, J Lourenco… - Cancer cell, 2024 - cell.com
Brain metastasis (BrM) is a common malignancy, predominantly originating from lung,
melanoma, and breast cancers. The vasculature is a key component of the BrM tumor …
melanoma, and breast cancers. The vasculature is a key component of the BrM tumor …
Nanotechnology-based gene therapy as a credible tool in the treatment of Alzheimer's disease
Toxic aggregated amyloid-β accumulation is a key pathogenic event in Alzheimer's disease.
Treatment approaches have focused on the suppression, deferral, or dispersion of amyloid …
Treatment approaches have focused on the suppression, deferral, or dispersion of amyloid …
Cellular mechanisms of fibrin (ogen): insight from neurodegenerative diseases
T Wen, Z Zhang - Frontiers in Neuroscience, 2023 - frontiersin.org
Neurodegenerative diseases are prevalent and currently incurable conditions that
progressively impair cognitive, behavioral, and psychiatric functions of the central or …
progressively impair cognitive, behavioral, and psychiatric functions of the central or …
Advances in Antioxidant Nanomedicines for Imaging and Therapy of Alzheimer's Disease
Significance: Reactive oxygen species (ROS) are crucial signaling molecules in the
regulation of numerous physiological activities including the formation and function of the …
regulation of numerous physiological activities including the formation and function of the …
Feasibility of diffusion‐tensor and correlated diffusion imaging for studying white‐matter microstructural abnormalities: application in COVID‐19
There has been growing attention on the effect of COVID‐19 on white‐matter microstructure,
especially among those that self‐isolated after being infected. There is also immense …
especially among those that self‐isolated after being infected. There is also immense …
Neurovascular unit pathology is observed very early in disease progression in the mutant SOD1G93A mouse model of amyotrophic lateral sclerosis
M Yoshikawa, S Aizawa, RW Oppenheim… - Experimental …, 2022 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a debilitating neurodegenerative disease
characterized by motor neuron degeneration that causes neuromuscular denervation …
characterized by motor neuron degeneration that causes neuromuscular denervation …
Multimodal imaging of the role of hyperglycemia following experimental subarachnoid hemorrhage
A Joya, S Plaza-García, D Padro… - Journal of Cerebral …, 2024 - journals.sagepub.com
Hyperglycemia has been linked to worsening outcomes after subarachnoid hemorrhage
(SAH). Nevertheless, the mechanisms involved in the pathogenesis of SAH have been …
(SAH). Nevertheless, the mechanisms involved in the pathogenesis of SAH have been …
Systematic oxidative stress indices predicts prognosis in patients with urothelial carcinoma of the upper urinary tract after radical nephroureterectomy
J Liu, S Lai, P Wu, J Wang, J Wang, J Wang… - European Journal of …, 2023 - Springer
Background Oxidative stress plays an important role in the occurrence and development of
malignancy. However, the relationship between oxidative stress and upper urinary tract …
malignancy. However, the relationship between oxidative stress and upper urinary tract …