The global population is aging and age-related cardiovascular disease is increasing. Even
after controlling for cardiovascular risk factors, readmission and mortality rates remain high …

Probiotics are considered to represent important modulators of gastrointestinal health
through increased colonization of beneficial bacteria thus altering the gut microflora …

Red ginseng, widely used in traditional medicine for various conditions, imparts health
benefits mainly by modulating the gut microbiota in humans. Given the similarities in gut …

High altitude is closely related to intestinal mucosal damage and intestinal microbiota
imbalance, and there is currently no effective prevention and treatment measures. In this …

Background The elevated circulating toxins secondary to the impairment of intestinal barrier
integrity commonly elicit a chronic inflammatory response and finally contribute to multiple …

Background The widely accepted microbiome-gut-brain axis (MGBA) hypothesis may be
essential for explaining the impact of high-altitude exposure on the human body, especially …

Cardiac allograft rejection remains a major factor limiting long-term engraftment after
transplantation. A novel phosphoinositide 3-kinase (PI3K)/mTOR dual inhibitor, BEZ235 …

Hyperactivation of hypothalamic–pituitary–adrenal (HPA) axis and hypothalamic–pituitary–
thyroid (HPT) axis were found in acute high altitude challenge, but the role of gut microbiota …

Cardiovascular function and adipose metabolism were markedly influenced under high
altitudes. However, the interplay between adipokines and heart under hypoxia remains to be …

Acute mountain sickness (AMS) is a common ailment in high-altitude areas caused by the
body's inadequate adaptation to low-pressure, low-oxygen environments, leading to organ …