Cholesterol is an essential structural component of membranes that contributes to
membrane integrity and fluidity. Cholesterol homeostasis plays a critical role in the …

Atherosclerosis, the pathological basis of most cardiovascular disease (CVD), is closely
associated with cholesterol accumulation in the arterial intima. Excessive cholesterol is …

The human genome encodes thousands of long noncoding RNAs (lncRNAs), the majority of
which are poorly conserved and uncharacterized. Here we identify a primate-specific …

Atherosclerosis is a leading cause of cardiovascular disease worldwide, and
hypercholesterolemia is a major risk factor. Preventive treatments mainly focus on the …

Atherosclerosis is a major cause of human cardiovascular disease, which is the leading
cause of mortality around the world. Various physiological and pathological processes are …

Atherosclerotic cardiovascular disease remains the leading cause of morbidity and mortality
worldwide. Atherosclerosis develops over several decades and is mediated by a complex …

Tumor cells show high avidity for cholesterol in order to support their inherent nature to
divide and proliferate. This results in the rewiring of cholesterol homeostatic pathways by …

MicroRNAs, as non-coding transcripts, modulate gene expression through RNA silencing
under normal physiological conditions. Their aberrant expression has strongly associated …

MicroRNAs are small noncoding RNAs that regulate gene expression at the
posttranscriptional level. Since many microRNAs have multiple mRNA targets, they are …

Atherosclerosis is a hallmark of cardiovascular disease, and lifestyle strongly impacts its
onset and progression. Nutrients have been shown to regulate the miR-17/92 cluster, with a …