Inhibitors of the mitochondrial citrate transport protein: validation of the role of substrate binding residues and discovery of the first purely competitive inhibitor

S Aluvila, J Sun, DHT Harrison, DE Walters… - Molecular …, 2010 - ASPET
The mitochondrial citrate transport protein (CTP) is critical to energy metabolism in
eukaryotic cells. We demonstrate that 1, 2, 3-benzenetricarboxylate (BTC), the classic and …

Glutaminolysis in animal cells

WL McKeehan - Carbohydrate metabolism in cultured cells, 1986 - Springer
Glutamine is the most abundant amino acid in plasma and most tissues (Van Slyke et al.,
1943). Because of both empirical reasoning and cellular requirements determined …

Inhibitors of mitochondrial anion transport

J Bry - Pharmacology & Therapeutics, 1980 - Elsevier
Compartmentation of metabolic processes between the cytosol and mitochondria, by virtue
of the cellular location of specific enzymes and the impermeability of the mitochondrial …

Intracellular distribution of phosphoenolpyruvate carboxylase and (NADP) malate dehydrogenase in different muscle types

J Nolte, D Brdiczka, D Pette - Biochimica et Biophysica Acta (BBA) …, 1972 - Elsevier
The intra-and extramitochondrial distribution of phosphoenolpyruvate carboxylase (GTP:
oxaloacetate carboxylase (transphosphorylating), EC 4.1. 1.32) and (NADP) malate …

The effects of cycloheximide on energy transfer in rat and guinea pig liver mitochondria

AJ Garber, M Jomain-Baum, L Salganicoff… - Journal of Biological …, 1973 - Elsevier
Cycloheximide was found to inhibit rat and guinea pig liver mitochondrial respiration in State
3 and after uncoupling by carbonyl cyanide p-trifluoromethoxyphenylhydrazone, although …

[PDF][PDF] On the specificity of the tricarboxylate carrier system in rat liver mitochondria

J Kleineke, H Sauer, HD Soling - FEBS Lett, 1973 - core.ac.uk
The transport of trivalent anions across the inner membrane of rat liver mitochondria is
mediated by a specific carrier system which catalyses an exchange of an external …

Synthesis of malate from phosphoenolpyruvate by rabbit liver mitochondria: implications for lipogenesis

BD Calsen, DO Lambeth, PD Ray - Biochimica et Biophysica Acta (BBA) …, 1988 - Elsevier
Rabbit liver mitochondria can convert exogenous phosphoenolpyruvate to malate.(2) Malate
production is dependent on phosphoenolpyruvate and HCO 3− and is stimulated by CN− or …

Synthesis of citrate from phosphoenolpyruvate and acetylcarnitine by mitochondria from rabbit, pigeon and rat liver: Implications for lipogenesis

TJ Wiese, SA Wuensch, PD Ray - … and Physiology Part B: Biochemistry and …, 1996 - Elsevier
Rabbit, pigeon and rat liver mitochondria convert exogenous phosphoenolpyruvate and
acetylcarnitine to citrate at rates of 14, 74 and 8 nmol/15 min/mg protein. Citrate formation is …

Role of the mitochondrial anion transporters in the regulation of ammoniagenesis in renal cortex mitochondria of the rabbit and rat

S CHEEMA‐DHADLI… - European Journal of …, 1979 - Wiley Online Library
The purpose of this study was to investigate factors which may regulate ammoniagenesis in
the kidney cortex. Emphasis was placed on the segment of the pathway by which the …

Glutamate transport by plant mitochondria

DA Day, JT Wiskich - Plant Science Letters, 1977 - Elsevier
The preparation of glutamate into isolated plant mitochondria was investigated using the
ammonium salt swelling technique. Glutamate entry required the presence of both …