Abstract MALDI-TOF MS technique is commonly used in system biology and clinical studies
to search for new potential markers associated with pathological conditions. Despite …

Epidermal growth factor receptor (EGFR) T790M mutation is the most frequent mechanism
which accounts for about 60% of acquired resistance to first-generation EGFR tyrosine …

The discovery of potent EGFR-tyrosine kinase inhibitors (EGFR-TKIs) has revolutionized the
treatment of EGFR-mutated lung cancer. Despite the fact that EGFR-TKIs have yielded …

Estimating the postmortem interval (PMI) is very important in the forensic sciences. Although
many approaches have been used for estimating the PMI, accurate PMI calculations are still …

Estimation of the postmortem interval (PMI) is a complicated task in forensic medicine,
especially during homicide and unwitnessed death investigations. Many biological …

Background Currently, no effective measures are available to predict the curative efficacy of
small-cell lung cancer (SCLC) chemotherapy. We expect to develop a method for effectively …

Background. Diagnoses of malignant pleural effusion (MPE) are a crucial problem in clinics.
In our study, we compared the peptide profiles of MPE and tuberculosis pleural effusion …

In the proteomic and genomic era, lung cancer researchers are increasingly under
challenge with traditional protein analyzing tools. High output, multiplexed analytical …

背景与目的本研究旨在应用基质辅助激光解析离子化-时间飞行质谱仪(matrix-assisted laser
desorption ionization time-of-flight mass spectrometry, MALDI-TOF-MS) …

本文旨在介绍外周血样品应用扩增阻滞突变系统(ARMS 法) 检测EGFR 基因突变的操作流程,
以及在实际操作中可能遇到的问题, 并对外周血检测EGFR 基因的应用和优缺点进行总结. 1 …