Clinical insights into small cell lung cancer: Tumor heterogeneity, diagnosis, therapy, and future directions

Z Megyesfalvi, CM Gay, H Popper… - CA: a cancer journal …, 2023 - Wiley Online Library
Small cell lung cancer (SCLC) is characterized by rapid growth and high metastatic capacity.
It has strong epidemiologic and biologic links to tobacco carcinogens. Although the majority …

Non-coding RNA-directed therapeutics in lung cancer: delivery technologies and clinical applications

AAH Abdellatif, G Scagnetti, MA Younis… - Colloids and Surfaces B …, 2023 - Elsevier
Lung cancer is one of the most aggressive and deadliest health threats. There has been an
increasing interest in non-coding RNA (ncRNA) recently, especially in the areas of …

[HTML][HTML] Cryobiopsy: a breakthrough strategy for clinical utilization of lung cancer organoids

D Park, D Lee, Y Kim, Y Park, YJ Lee, JE Lee, MK Yeo… - Cells, 2023 - mdpi.com
One major challenge associated with lung cancer organoids (LCOs) is their predominant
derivation from surgical specimens of patients with early-stage lung cancer. However …

Recent frontiers in biofabrication for respiratory tissue engineering

A Zimmerling, NA Dahlan, Y Zhou, X Chen - Bioprinting, 2024 - Elsevier
Respiratory tissue engineering offers a robust framework for studying cell-cell and host-
pathogen interactions in a tissue-like environment and offers a platform for studying lung …

[PDF][PDF] Moving toward precision medicine with lung cancer organoids

J Kim, JD Minna - Cell Reports Medicine, 2023 - cell.com
Moving toward precision medicine with lung cancer organoids Page 1 Preview Moving
toward precision medicine with lung cancer organoids James Kim1,2,4,* and John D. Minna1,2,3,4 …

[HTML][HTML] The role of patient-derived organoids in triple-negative breast cancer drug screening

I Psilopatis, A Mantzari, K Vrettou, S Theocharis - Biomedicines, 2023 - mdpi.com
Triple-negative breast cancer (TNBC) is one of the most aggressive breast cancer subtypes,
with a grave prognosis and few effective treatment options. Organoids represent …

[PDF][PDF] Applied models and molecular characteristics of small cell lung cancer

GM Fűr, K Nemes, É Magó, AÁ Benő… - Pathology and …, 2024 - por-journal.com
Small Cell Lung Cancer (SCLC) is an extremely aggressive form of cancer, accounting for
about 15% of all lung cancer cases. Due to its aggressive nature, over 60% of SCLC cases …

[HTML][HTML] Cell Culture Model Evolution and Its Impact on Improving Therapy Efficiency in Lung Cancer

V Roman, M Mihaila, N Radu, S Marineata… - Cancers, 2023 - mdpi.com
Simple Summary The lack of models capable of reproducing the cellular mechanisms
responsible for cancer progression in vivo makes it difficult to develop effective anticancer …

[HTML][HTML] In vitro vascularized immunocompetent patient-derived model to test cancer therapies

H Lê, J Deforges, G Hua, Y Idoux-Gillet, C Ponté… - Iscience, 2023 - Elsevier
This work describes a patient-derived tumoroid model (PDTs) to support precision medicine
in lung oncology. The use of human adipose tissue-derived microvasculature and patient …

[HTML][HTML] Zebrafish in Lung Cancer Research

X Wu, X Hua, K Xu, Y Song, T Lv - Cancers, 2023 - mdpi.com
Simple Summary Zebrafish is a crucial in vivo model for lung cancer research and is widely
employed in studies focusing on cancer proliferation, metastasis, and angiogenesis. It plays …