Clinical insights into small cell lung cancer: Tumor heterogeneity, diagnosis, therapy, and future directions
Z Megyesfalvi, CM Gay, H Popper… - CA: a cancer journal …, 2023 - Wiley Online Library
Small cell lung cancer (SCLC) is characterized by rapid growth and high metastatic capacity.
It has strong epidemiologic and biologic links to tobacco carcinogens. Although the majority …
It has strong epidemiologic and biologic links to tobacco carcinogens. Although the majority …
Non-coding RNA-directed therapeutics in lung cancer: delivery technologies and clinical applications
AAH Abdellatif, G Scagnetti, MA Younis… - Colloids and Surfaces B …, 2023 - Elsevier
Lung cancer is one of the most aggressive and deadliest health threats. There has been an
increasing interest in non-coding RNA (ncRNA) recently, especially in the areas of …
increasing interest in non-coding RNA (ncRNA) recently, especially in the areas of …
[HTML][HTML] Cryobiopsy: a breakthrough strategy for clinical utilization of lung cancer organoids
One major challenge associated with lung cancer organoids (LCOs) is their predominant
derivation from surgical specimens of patients with early-stage lung cancer. However …
derivation from surgical specimens of patients with early-stage lung cancer. However …
Recent frontiers in biofabrication for respiratory tissue engineering
Respiratory tissue engineering offers a robust framework for studying cell-cell and host-
pathogen interactions in a tissue-like environment and offers a platform for studying lung …
pathogen interactions in a tissue-like environment and offers a platform for studying lung …
[PDF][PDF] Moving toward precision medicine with lung cancer organoids
J Kim, JD Minna - Cell Reports Medicine, 2023 - cell.com
Moving toward precision medicine with lung cancer organoids Page 1 Preview Moving
toward precision medicine with lung cancer organoids James Kim1,2,4,* and John D. Minna1,2,3,4 …
toward precision medicine with lung cancer organoids James Kim1,2,4,* and John D. Minna1,2,3,4 …
[HTML][HTML] The role of patient-derived organoids in triple-negative breast cancer drug screening
I Psilopatis, A Mantzari, K Vrettou, S Theocharis - Biomedicines, 2023 - mdpi.com
Triple-negative breast cancer (TNBC) is one of the most aggressive breast cancer subtypes,
with a grave prognosis and few effective treatment options. Organoids represent …
with a grave prognosis and few effective treatment options. Organoids represent …
[PDF][PDF] Applied models and molecular characteristics of small cell lung cancer
GM Fűr, K Nemes, É Magó, AÁ Benő… - Pathology and …, 2024 - por-journal.com
Small Cell Lung Cancer (SCLC) is an extremely aggressive form of cancer, accounting for
about 15% of all lung cancer cases. Due to its aggressive nature, over 60% of SCLC cases …
about 15% of all lung cancer cases. Due to its aggressive nature, over 60% of SCLC cases …
[HTML][HTML] Cell Culture Model Evolution and Its Impact on Improving Therapy Efficiency in Lung Cancer
Simple Summary The lack of models capable of reproducing the cellular mechanisms
responsible for cancer progression in vivo makes it difficult to develop effective anticancer …
responsible for cancer progression in vivo makes it difficult to develop effective anticancer …
[HTML][HTML] In vitro vascularized immunocompetent patient-derived model to test cancer therapies
H Lê, J Deforges, G Hua, Y Idoux-Gillet, C Ponté… - Iscience, 2023 - Elsevier
This work describes a patient-derived tumoroid model (PDTs) to support precision medicine
in lung oncology. The use of human adipose tissue-derived microvasculature and patient …
in lung oncology. The use of human adipose tissue-derived microvasculature and patient …
[HTML][HTML] Zebrafish in Lung Cancer Research
X Wu, X Hua, K Xu, Y Song, T Lv - Cancers, 2023 - mdpi.com
Simple Summary Zebrafish is a crucial in vivo model for lung cancer research and is widely
employed in studies focusing on cancer proliferation, metastasis, and angiogenesis. It plays …
employed in studies focusing on cancer proliferation, metastasis, and angiogenesis. It plays …