The treatment of rheumatoid arthritis using Chinese medicinal plants: from pharmacology to potential molecular mechanisms

S Lü, Q Wang, G Li, S Sun, Y Guo, H Kuang - Journal of …, 2015 - Elsevier
Ethnopharmacological relevance Rheumatoid arthritis (RA) is a common worldwide public
health problem. Traditional Chinese Medicine (TCM) achieved some results to some extent …

[HTML][HTML] Systematic review of robust experimental models of rheumatoid arthritis for basic research

L Ye, H Mingyue, Z Feng, D Zongshun, X Ying… - Digital Chinese …, 2021 - Elsevier
Rheumatoid arthritis (RA) is a common autoimmune disease characterized by progressive
joint inflammation and destruction, deformity, loss of mobility, and permanent disability …

Adjuvants-and vaccines-induced autoimmunity: animal models

JT Ruiz, L Luján, M Blank, Y Shoenfeld - Immunologic research, 2017 - Springer
The emergence of autoimmunity after vaccination has been described in many case reports
and series. Everyday there is more evidence that this relationship is more than casual. In …

RNF138 inhibits late inflammatory gene transcription through degradation of SMARCC1 of the SWI/SNF complex

W Liu, Z Wang, S Liu, X Zhang, X Cao, M Jiang - Cell Reports, 2023 - cell.com
As one of the core components of the switching or sucrose non-fermentable (SWI/SNF)
complex, SMARCC1 (BAF155, SRG3) plays essential roles in activation of late inflammatory …

Slc11a1 (Nramp-1) gene modulates immune-inflammation genes in macrophages during pristane-induced arthritis in mice

MA Correa, T Canhamero, A Borrego, ISS Katz… - Inflammation …, 2017 - Springer
Objective and design Pristane-induced arthritis (PIA) in AIRmax mice homozygous for
Slc11a1 R and S alleles was used to characterize the influence of Slc11a1 gene …

Bioinformatic identification of hub genes and key pathways in neutrophils of patients with acute respiratory distress syndrome

L Hu, T Zhao, Y Sun, Y Chen, K Bai, F Xu - Medicine, 2020 - journals.lww.com
Acute respiratory distress syndrome (ARDS) is characterized as a neutrophil-dominant
disorder without effective pharmacological interventions. Knowledge of neutrophils in ARDS …

Identification of key biomarkers and immune infiltration in the thoracic acute aortic dissection by bioinformatics analysis

J Luo, H Shi, H Ran, C Zhang, Q Wu, Y Shao - BMC Cardiovascular …, 2023 - Springer
Background Thoracic acute aortic dissection (TAAD), one of the most fatal cardiovascular
diseases, leads to sudden death, however, its mechanism remains unclear. Methods Three …

Slc11a1 gene polymorphism influences dextran sulfate sodium (DSS)-induced colitis in a murine model of acute inflammation

STQ de Andrade, TI Guidugli, A Borrego… - Genes & …, 2023 - nature.com
Ulcerative Colitis (UC) is an inflammatory disease characterized by colonic mucosal lesions
associated with an increased risk of carcinogenesis. UC pathogenesis involves …

The role of NRAMP1/SLC11A1 gene variant D543N (1730G/A) in the genetic susceptibility to develop Rheumatoid arthritis in the Mexican Mestizo population

P Niño-Moreno, E Turrubiartes-Martínez… - Revista de …, 2017 - medigraphic.com
Background: Rheumatoid arthritis is a chronic inflammatory disease whose cause has not
been fully elucidated. However, genetic factors seem to have an important role in its …

Trypanosoma cruzi Infection in Genetically Selected Mouse Lines: Genetic Linkage with Quantitative Trait Locus Controlling Antibody Response

F Vorraro, WHK Cabrera, OG Ribeiro… - Mediators of …, 2014 - Wiley Online Library
Trypanosoma cruzi infection was studied in mouse lines selected for maximal (AIRmax) or
minimal (AIRmin) acute inflammatory reaction and for high (HIII) or low (LIII) antibody (Ab) …