Ohtahara syndrome (OS) is well known as a peculiar early onset epileptic syndrome with
serious prognosis. The outline of OS, mainly in relation to the evolution with age, and …

Infantile spasms is one of the “catastrophic childhood epilepsies” because of the difficulty in
controlling seizures and the association with mental retardation. However, early recognition …

We examined a number of Drosophila mutants with increased susceptibility to seizures
following mechanical or electrical stimulation to better understand the underlying factors that …

Background Neurogenetic developmental conditions represent a heterogeneous group of
rare inherited disorders with neurological manifestation during development. Treatments for …

The term epileptic encephalopathy is used to describe diffuse brain dysfunction that is
caused, at least in part, by some aspect of epilepsy. Early-infantile epileptic encephalopathy …

Seizures during the neonatal period are always medical emergencies. Apart from the need
for rapid anticonvulsive treatment, the underlying condition is often not immediately obvious …

This book analyses the impact of epilepsy that develops in childhood. As sufferers of
epilepsy move from childhood into adulthood, the shift in primary responsibility for their …

Purpose: The pentylenetetrazol (PTZ) infusion test was used to compare seizure thresholds
in adult and young rats fed either a 4: 1 ketogenic diet (KD) or a 6.3: 1 KD. We hypothesized …

Inborn errors of metabolism (IEM) are a heterogeneous group of rare genetic disorders that
are generally transmitted as autosomal or X-linked recessive disorders. These defects arise …

Background: Neonatal seizures (NS) affect approximately 1% of neonates. Clonic, tonic,
myoclonic and subtle seizures are the common types. Birth asphyxia, sepsis, metabolic …