[HTML][HTML] Regulatory mechanisms and therapeutic implications of insulin-like growth factor 2 mRNA-binding proteins, the emerging crucial m6A regulators of tumors
H Zhou, Q Sun, M Feng, Z Gao, S Jia, L Cao, X Yu… - Theranostics, 2023 - ncbi.nlm.nih.gov
Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs) serve essential biological
functions as post-transcriptional performers, participating in the acquisition or maintenance …
functions as post-transcriptional performers, participating in the acquisition or maintenance …
Lactylation stabilizes DCBLD1 activating the pentose phosphate pathway to promote cervical cancer progression
Q Meng, H Sun, Y Zhang, X Yang, S Hao, B Liu… - Journal of Experimental …, 2024 - Springer
Abstract Background Discoidin, CUB, and LCCL domain-containing type I (DCBLD1) is
identified as an oncogene involved in multiple regulation of tumor progression, but specific …
identified as an oncogene involved in multiple regulation of tumor progression, but specific …
Autophagy in cancer immunotherapy: Perspective on immune evasion and cell death interactions
Q Yu, J Ding, S Li, Y Li - Cancer Letters, 2024 - Elsevier
Both the innate and adaptive immune systems work together to produce immunity. Cancer
immunotherapy is a novel approach to tumor suppression that has arisen in response to the …
immunotherapy is a novel approach to tumor suppression that has arisen in response to the …
Autophagy machinery in glioblastoma: The prospect of cell death crosstalk and drug resistance with bioinformatics analysis
Brain tumors are common malignancies with high mortality and morbidity in which
glioblastoma (GB) is a grade IV astrocytoma with heterogeneous nature. The conventional …
glioblastoma (GB) is a grade IV astrocytoma with heterogeneous nature. The conventional …
LncRNA PRBC induces autophagy to promote breast cancer progression through modulating PABPC1-mediated mRNA stabilization
Y Liang, B Chen, F Xu, L Long, F Ye, Y Wang, D Luo… - Oncogene, 2024 - nature.com
Breast cancer is one of the major malignant tumors among women worldwide. Long
noncoding RNAs (lncRNAs) have been documented as significant modulators in the …
noncoding RNAs (lncRNAs) have been documented as significant modulators in the …
Kidney-targeted antioxidant salvianolic acid B nanoparticles restoring lysosome homeostasis for acute kidney injury therapy
JL Chen, XH Jia, X Wu, MH Yuan, X Xia, D Yin… - Chemical Engineering …, 2024 - Elsevier
Acute kidney injury (AKI) is highly correlated with oxidative stress, and the application of
antioxidants is one of the promising treatments. Salvianolic acid B (SAB) is a natural …
antioxidants is one of the promising treatments. Salvianolic acid B (SAB) is a natural …
Ginsenoside Rk1 induces autophagy-dependent apoptosis in hepatocellular carcinoma by AMPK/mTOR signaling pathway
H Wu, L Qu, X Bai, C Zhu, Y Liu, Z Duan, H Liu… - Food and Chemical …, 2024 - Elsevier
Hepatocellular carcinoma (HCC) is the third most lethal cancer in the world. Recent studies
have shown that suppression of autophagy plays an important role in the development of …
have shown that suppression of autophagy plays an important role in the development of …
Caffeic acid phenethyl ester promotes oxaliplatin sensitization in colon cancer by inhibiting autophagy
F Xing, N Liu, C Wang, XD Wang - Scientific Reports, 2024 - nature.com
Colon cancer ranks as the third most prevalent form of cancer globally, with chemotherapy
remaining the primary treatment modality. To mitigate drug resistance and minimize adverse …
remaining the primary treatment modality. To mitigate drug resistance and minimize adverse …
Advanced coacervation-driven nanoscale polymeric assemblies for biomedical applications
L Shu, Y Gong, M Lin, J Sun, X Chen - Applied Physics Reviews, 2024 - pubs.aip.org
Complex coacervation, a fascinating phenomenon rooted in liquid–liquid phase separation,
plays a crucial role in numerous biological systems. This intricate process involves the …
plays a crucial role in numerous biological systems. This intricate process involves the …
Targeting PNPO to suppress tumor growth via inhibiting autophagic flux and to reverse paclitaxel resistance in ovarian cancer
X Li, W Guan, H Liu, J Yuan, F Wang, B Guan, J Chen… - Apoptosis, 2024 - Springer
Our previous study showed that pyridoxine 5'-phosphate oxidase (PNPO) is a tissue
biomarker of ovarian cancer (OC) and has a prognostic implication but detailed mechanisms …
biomarker of ovarian cancer (OC) and has a prognostic implication but detailed mechanisms …