[HTML][HTML] Neurogenesis from embryo to adult–lessons from flies and mice
The human brain is composed of billions of cells, including neurons and glia, with an
undetermined number of subtypes. During the embryonic and early postnatal stages, the …
undetermined number of subtypes. During the embryonic and early postnatal stages, the …
Adding a spatial dimension to postnatal ventricular-subventricular zone neurogenesis
R Fiorelli, K Azim, B Fischer, O Raineteau - Development, 2015 - journals.biologists.com
Neurogenesis does not stop abruptly at birth, but persists in specific brain regions
throughout life. The neural stem cells (NSCs) located in the largest germinal region of the …
throughout life. The neural stem cells (NSCs) located in the largest germinal region of the …
[PDF][PDF] Single-cell analysis of regional differences in adult V-SVZ neural stem cell lineages
D Mizrak, HM Levitin, AC Delgado, V Crotet, J Yuan… - Cell reports, 2019 - cell.com
The ventricular-subventricular zone (V-SVZ) harbors adult neural stem cells. V-SVZ neural
stem cells exhibit features of astrocytes, have a regional identity, and depending on their …
stem cells exhibit features of astrocytes, have a regional identity, and depending on their …
Single-cell analysis of the postnatal dorsal V-SVZ reveals a role for Bmpr1a signaling in silencing pallial germinal activity
G Marcy, L Foucault, E Babina, T Capeliez… - Science …, 2023 - science.org
The ventricular-subventricular zone (V-SVZ) is the largest neurogenic region of the postnatal
forebrain, containing neural stem cells (NSCs) that emerge from both the embryonic pallium …
forebrain, containing neural stem cells (NSCs) that emerge from both the embryonic pallium …
Quiescent neural stem cells for brain repair and regeneration: lessons from model systems
Neural stem cells (NSCs) are multipotent progenitors that are responsible for producing all
of the neurons and macroglia in the nervous system. In adult mammals, NSCs reside …
of the neurons and macroglia in the nervous system. In adult mammals, NSCs reside …
[PDF][PDF] Persistent expression of VCAM1 in radial glial cells is required for the embryonic origin of postnatal neural stem cells
During development, neural stem cells (NSCs) undergo transitions from neuroepithelial cells
to radial glial cells (RGCs), and later, a subpopulation of slowly dividing RGCs gives rise to …
to radial glial cells (RGCs), and later, a subpopulation of slowly dividing RGCs gives rise to …
Pharmacogenomic identification of small molecules for lineage specific manipulation of subventricular zone germinal activity
K Azim, D Angonin, G Marcy, F Pieropan, A Rivera… - PLoS …, 2017 - journals.plos.org
Strategies for promoting neural regeneration are hindered by the difficulty of manipulating
desired neural fates in the brain without complex genetic methods. The subventricular zone …
desired neural fates in the brain without complex genetic methods. The subventricular zone …
[PDF][PDF] HOPX defines heterogeneity of postnatal subventricular zone neural stem cells
S Zweifel, G Marcy, QL Guidice, D Li, C Heinrich… - Stem cell reports, 2018 - cell.com
The largest diversity of neural lineages generated from the subventricular zone (SVZ) occurs
early after birth and is regulated in a spatiotemporal manner depending on the expression of …
early after birth and is regulated in a spatiotemporal manner depending on the expression of …
Neural stem cells in the adult olfactory bulb core generate mature neurons in vivo
Ç Defteralı, M Moreno-Estellés, C Crespo… - Stem Cells, 2021 - academic.oup.com
Although previous studies suggest that neural stem cells (NSCs) exist in the adult olfactory
bulb (OB), their location, identity, and capacity to generate mature neurons in vivo has been …
bulb (OB), their location, identity, and capacity to generate mature neurons in vivo has been …
Targeting the subventricular zone to promote myelin repair in the aging brain
AM Butt, AD Rivera, D Fulton, K Azim - Cells, 2022 - mdpi.com
The subventricular zone (SVZ) is the largest and most active germinal zone in the adult
forebrain. Neural stem cells (NSCs) of the SVZ generate olfactory interneurons throughout …
forebrain. Neural stem cells (NSCs) of the SVZ generate olfactory interneurons throughout …