Emerging concepts in the areas related to the pathogenesis and treatment of atopic
dermatitis are reviewed. In particular, recent findings have revealed several key steps in the …

The immune system may either have a protective role against sunburn and skin cancer or,
conversely, promote solar damage. The skin is poised to react to infections and injury, such …

We investigated epidermal cell suspensions prepared from lesional and nonlesional atopic
eczema skin, other inflammatory skin conditions, and normal human skin for high-affinity IgE …

Animal models of hematopoietic stem cell transplantation have been used to analyze the
turnover of bone marrow–derived cells and to demonstrate the critical role of recipient …

Background: The skin is repeatedly exposed to solar UV radiation. Long-term photodamage
is a consequence of cumulative UV radiation injury. Hence an examination of the repetitive …

In a double-blind trial, 21 patients with severe plaque psoriasis were randomly assigned to
receive oral cyclosporine, 14 mg/kg/d, or its vehicle. After four weeks of therapy the 11 …

Increasing UVB radiation at the earth's surface might have adverse effects on in vivo
immunologic responses in humans. We prospectively randomized subjects to test whether …

The immunocytochemical identification and characterization of indigenous dermal dendritic
cells (dermal dendrocytes) using a rabbit polyclonal antibody to clotting enzyme factor XIII …

Human skin apart from functioning as a physical barricade to stop the entry of pathogens,
also hosts innumerable commensal organisms. The skin cells and the immune system …

Cyclosporine inhibits the activation of helper T cells that may be pathogenic in alopecia
areata Therefore we treated six patients with alopecia areata (five men, one woman) with …