Interplay of environmental signals and progenitor diversity on fate specification of cortical GABAergic neurons

JA Brandão, RN Romcy-Pereira - Frontiers in cellular neuroscience, 2015 - frontiersin.org
Cortical GABAergic interneurons constitute an extremely diverse population of cells
organized in a well-defined topology of precisely interconnected cells. They play a crucial …

A mutation in monoamine oxidase (MAO) affects the evolution of stress behavior in the blind cavefish Astyanax mexicanus

C Pierre, N Pradère, C Froc… - Journal of …, 2020 - journals.biologists.com
The neurotransmitter serotonin controls a variety of physiological and behavioral processes.
In humans, mutations affecting monoamine oxidase (MAO), the serotonin-degrading …

Maternal serotonin: shaping developmental patterns and behavioral strategy on progeny in molluscs

EE Voronezhskaya - Frontiers in Ecology and Evolution, 2021 - frontiersin.org
Serotonin is a well-known neurotransmitter and neurohormone regulating mood, sleep,
feeding, and learning in high organisms. Serotonin also affects the embryonic events related …

The Human Serotonin Type 3 Receptor Gene (HTR3A‐E) Allelic Variant Database

J Celli, G Rappold, B Niesler - Human mutation, 2017 - Wiley Online Library
ABSTRACT Serotonin type 3 (5‐HT3) receptors are ligand‐gated ion channels formed by
five subunits (5‐HT3A‐E), which are encoded by the HTR3A, HTR3B, HTR3C, HTR3D, and …

Contribution of the serotonergic system to developmental brain abnormalities in autism spectrum disorder

J Wegiel, K Chadman, E London… - Autism …, 2024 - Wiley Online Library
This review highlights a key role of the serotonergic system in brain development and in
distortions of normal brain development in early stages of fetal life resulting in cascades of …

The serotonin receptor 3E variant is a risk factor for female IBS-D

N Fritz, S Berens, Y Dong, C Martínez… - Journal of Molecular …, 2022 - Springer
Irritable bowel syndrome (IBS) is a gut-brain disorder of multifactorial origin. Evidence of
disturbed serotonergic function in IBS accumulated for the 5-HT3 receptor family. 5-HT3Rs …

Editorial perspective of the Research Topic “Deciphering serotonin's role in neurodevelopment”

JR Homberg, SM Kolk, D Schubert - Frontiers in cellular …, 2013 - frontiersin.org
Serotonin is implicated in many, if not all, psychiatric disorders and is therefore the most
studied neurotransmitter in our brain. Nevertheless, the developing serotonergic system and …

Impact of pharmacological and non-pharmacological modulators on dendritic spines structure and functions in brain

AM Mahalakshmi, B Ray, S Tuladhar, TA Hediyal… - Cells, 2021 - mdpi.com
Dendritic spines are small, thin, hair-like protrusions found on the dendritic processes of
neurons. They serve as independent compartments providing large amplitudes of Ca2+ …

Targeting gap junctions: new insights into the treatment of major depressive disorder

D Sarrouilhe, M Mesnil, C Dejean - Current Medicinal …, 2019 - ingentaconnect.com
Background: Major depressive disorder (MDD) is a multifactorial chronic and debilitating
mood disease with high lifetime prevalence and associated with excess mortality …

Catecholaminergic axons in the neocortex of adult mice regrow following brain injury

SE Dougherty, TJ Kajstura, Y Jin, MH Chan-Cortés… - Experimental …, 2020 - Elsevier
Serotonin axons in the adult rodent brain can regrow and recover their function following
several forms of injury including controlled cortical impact (CCI), a neocortical stab wound …