[HTML][HTML] The molecular genetics of PI3K/PTEN/AKT/mTOR pathway in the malformations of cortical development

Q Ma, G Chen, Y Li, Z Guo, X Zhang - Genes & Diseases, 2024 - Elsevier
Malformations of cortical development (MCD) are a group of developmental disorders
characterized by abnormal cortical structures caused by genetic or harmful environmental …

The roles of serotonin in cell adhesion and migration, and cytoskeletal remodeling

JAK John Jayakumar, MM Panicker - Cell Adhesion & Migration, 2021 - Taylor & Francis
Serotonin is well known as a neurotransmitter. Its roles in neuronal processes such as
learning, memory or cognition are well established, and also in disorders such as …

Chronic Treatment with Serotonin Selective Reuptake Inhibitors Does Not Affect Regrowth of Serotonin Axons Following Amphetamine Injury in the Mouse Forebrain

HN Janowitz, DJ Linden - Eneuro, 2024 - eneuro.org
A current hypothesis to explain the limited recovery following brain and spinal cord trauma
stems from the dogma that neurons in the mammalian central nervous system lack the ability …

Neuronal activity controls the development of interneurons in the somatosensory cortex

R Babij, N De Marco Garcia - Frontiers in biology, 2016 - Springer
BACKGROUND Neuronal activity in cortical areas regulates neurodevelopment by
interacting with defined genetic programs to shape the mature central nervous system …

Autism spectrum disorders pathogenesis: Toward a comprehensive model based on neuroanatomic and neurodevelopment considerations

A Beopoulos, M Géa, A Fasano, F Iris - Frontiers in Neuroscience, 2022 - frontiersin.org
Autism spectrum disorder (ASD) involves alterations in neural connectivity affecting cortical
network organization and excitation to inhibition ratio. It is characterized by an early increase …

Seasonality of plasma tryptophan and kynurenine in pregnant mothers with a history of seasonal affective disorder: Vulnerability or adaptation?

RD Levitan, M Sqapi, L Atkinson, K Murphy… - The World Journal of …, 2020 - Taylor & Francis
Objectives: Maternal-foetal tryptophan metabolism plays multiple roles in neurodevelopment
and immunomodulation across pregnancy. Tryptophan and the immune system are both …

Neurodevelopmental and behavioral consequences of perinatal exposure to the HIV drug efavirenz in a rodent model

L Van de Wijer, LP Garcia, SI Hanswijk, J Rando… - Translational …, 2019 - nature.com
Efavirenz is recommended as a preferred first-line drug for women of childbearing potential
living with human immunodeficiency virus. Efavirenz is known for its central nervous system …

Neuropharmacological and neurochemical evaluation of N-n-propyl-3-ethoxyquinoxaline-2-carboxamide (6n): a novel serotonergic 5-HT3 receptor antagonist for co …

S Bhatt, R Mahesh, A Jindal… - Journal of Basic and …, 2017 - degruyter.com
Background: Several preclinical studies have shown that serotonergic 5-HT3 receptor
antagonists play an important role in the management of neuropsychiatric disorders, such as …

Depletion of TrkB receptors from adult serotonergic neurons increases brain serotonin levels, enhances energy metabolism and impairs learning and memory

MP Sahu, Y Pazos-Boubeta, A Steinzeig… - Frontiers in Molecular …, 2021 - frontiersin.org
Neurotrophin brain-derived neurotrophic factor (BDNF) and neurotransmitter serotonin (5-
HT) regulate each other and have been implicated in several neuronal mechanisms …

Perinatal Fluoxetine Exposure Impairs the CO2 Chemoreflex. Implications for Sudden Infant Death Syndrome

K Bravo, JL Eugenín, I Llona - American Journal of Respiratory Cell …, 2016 - atsjournals.org
High serotonin levels during pregnancy affect central nervous system development. Whether
a commonly used antidepressant such as fluoxetine (a selective serotonin reuptake …