Neurotoxicity of MDMA: Main effects and mechanisms

G Costa, K Gołembiowska - Experimental neurology, 2022 - Elsevier
Preclinical and clinical studies indicate that 3, 4-methylenedioxymethamphetamine
(MDMA;'ecstasy'), in addition to having abuse potential, may elicit acute and persistent …

Lack of Rhes increases MDMA-induced neuroinflammation and dopamine neuron degeneration: Role of gender and age

G Costa, PF Porceddu, M Serra, MA Casu… - International journal of …, 2019 - mdpi.com
Ras homolog enriched in striatum (Rhes) is a protein that exerts important physiological
functions and modulates psychostimulant drug effects. On this basis, the object of this study …

[HTML][HTML] Cholinergic system and exploratory behavior are changed after weekly-binge ethanol exposure in zebrafish

HT Bernardo, JF Agostini, HCZ Dal Toé… - Pharmacology …, 2019 - Elsevier
Binge drinking is characterized by excessive alcohol consumption in a short period of time
and is associated with a poor quality of life. Zebrafish are commonly used to investigate …

Clinical profile of designer drug “Strox” intoxicated cases presented to Poison control center Ain Shams University, Egypt from first of January 2017 to end of January …

M El-Masry, S Abdelkader - Ain Shams Journal of Forensic Medicine …, 2021 - journals.ekb.eg
Introduction: Drug addiction is considered one of the serious problems. Clinical profile of
drug dependence is continuously changing taking new shape, new drugs and routes. From …

Amitriptyline Accelerates SERT Binding Recovery in a Rat 3,4-Methylenedioxymethamphetamine (MDMA) Model: In Vivo 4-[18F]-ADAM PET Imaging

CJ Tsai, CH Chiu, YY Kuo, WS Huang, TH Yu… - International journal of …, 2022 - mdpi.com
Numerous studies have confirmed that 3, 4-Methylenedioxymethamphetamine (MDMA)
produces long-lasting changes to the density of the serotonin reuptake transporter (SERT) …

Nicotine and modafinil combination protects against the neurotoxicity induced by 3, 4-Methylenedioxymethamphetamine in hippocampal neurons of male rats

G Kowsari, S Mehrabi, SS Asl, M Pourhamzeh… - Journal of Chemical …, 2021 - Elsevier
Abstract MDMA (3, 4-Methylenedioxymethamphetamine) is a common recreational drug of
abuse which causes neurodegeneration. Nicotine and modafinil provide antioxidant and …

Amitriptyline Accelerates SERT Binding Recovery Rate in MDMA-Induced Rat Model: In Vivo 4-[18F]-ADAM PET Imaging

SHH Yeh, CH Chiu, YY Kuo, CJ Tsai, TH Yu… - 2021 - researchsquare.com
Background Numerous studies have confirmed that 3, 4-Methylenedioxymethamphetamine
(MDMA) produces long-lasting changes to the serotonergic system and decreases the …

The Lethal and Toxic Effects of 3, 4-Methylenedioxymethamphetamine (MDMA) and Methylone in Combination with Alcohol or Nicotine

AOMB Gunaid - 2022 - search.proquest.com
Methylenedioxy-methamphetamine (MDMA) and 3, 4-methylenedioxy-N-methylcathinone
(Methylone) have been abused, particularly by teens and young adults. These drugs are …

[PDF][PDF] Investigator's Brochure

DCUTOFF DATE - cdn.mapspublicbenefit.com
There have been a number of serious incidents among individuals who use Ecstasy
(material represented as containing MDMA, as defined above) around the world in various …