Lipid nanoparticles (LNPs) are the most versatile and successful gene delivery systems,
notably highlighted by their use in vaccines against COVID-19. LNPs have a well-defined …

Cell membranes are very complex biological systems including a large variety of lipids and
proteins. Therefore, they are difficult to extract and directly investigate with biophysical …

Lipid nanoparticles (LNPs) are important delivery systems for RNA-based therapeutics, yet
the mechanism of their interaction with endosomal membranes remains unclear. Here, the …

Lipopolysaccharides (LPSs) are a constitutive element of the cell envelope of Gram-
negative bacteria, representing the main lipid in the external leaflet of their outer membrane …

The membrane is one of the key structural materials of biology at the cellular level.
Composed predominantly of a bilayer of lipids with embedded and bound proteins, it defines …

The complex composition of bacterial membranes has a significant impact on the
understanding of pathogen function and their development towards antibiotic resistance. In …

As a naturally occurring cytolytic peptide, melittin (MLT) not only exhibits a potent direct
tumor cell-killing effect but also possesses various immunomodulatory functions. MLT shows …

Developing more efficient manufacturing methods for nano therapeutic systems is becoming
important, not only to better control their physico-chemical characteristics and therapeutic …

Arrays of nanoparticle-supported lipid bilayers (nanoSLB) are lipid-coated nanopatterned
interfaces that provide a platform to study curved model biological membranes using surface …

Peptide–lipid interactions play an important role in defining the mode of action of drugs and
the molecular mechanism associated with many diseases. Model membranes consisting of …