Candida tropicalis is one of the most pathogenic species within the genus. Increased
antifungal resistance has been reported, which is in part due to the organism's ability to form …

The polyene antifungal amphotericin B (AmB) exerts a powerful and broad activity against a
vast array of fungi and in general displays a remarkably low rate of antimicrobial resistance …

Invasive fungal infections are a strong contributor to healthcare costs, morbidity and
mortality, especially amongst hospitalized patients. Historically, Candida was responsible for …

Iron is a key transition metal required by most microorganisms and is prominently utilised in
the transfer of electrons during metabolic reactions. The acquisition of iron is essential and …

Wireless electroceutical dressing (WED) fabric kills bacteria and disrupts bacterial biofilm.
This work tested, comparing with standard of care topical antibiotic ketoconazole, whether …

Mechanistic studies have shown that aggregates of a common membrane disrupting
molecule, Triton X-100, destroy the integrity of cholesterol-rich phospholipid bilayers via a …

Fungi cause serious nosocomial infections including candidiasis and aspergillosis, some of
which display reduced susceptibility to current antifungals. Inorganic compounds have been …

ABSTRACT Z inc c luster transcription f actors (Zcfs) encoding zcf genes are exclusive for
fungi and required for multiple cellular processes including metabolism and development …

Invasive aspergillosis caused by intrinsically resistant non-fumigatus Aspergillus species
displays a poor outcome in immunocompromised patients. The polyene antifungal …

Echinocandins, used for the prevention and treatment of invasive fungal infections, have led
to a rise in breakthrough infections caused by resistant Candida species. Among these …