SJNNV down-regulates RGNNV replication in European sea bass by the induction of the type I interferon system

C Carballo, E Garcia-Rosado, JJ Borrego… - Veterinary research, 2016 - Springer
European sea bass is highly susceptible to the betanodavirus RGNNV genotype, although
the SJNNV genotype has also been detected in this fish species. The coexistence of both …

Transcriptome analysis of rainbow trout in response to non-virion (NV) protein of viral haemorrhagic septicaemia virus (VHSV)

B Chinchilla, P Encinas, A Estepa, JM Coll… - Applied microbiology …, 2015 - Springer
The non-virion (NV) protein of viral haemorrhagic septicaemia virus (VHSV), an
economically important fish novirhabdovirus, has been implicated in the interference of …

Effect of the viral hemorrhagic septicemia virus nonvirion protein on translation via PERK-eIF2α pathway

SP Kesterson, J Ringiesn, VN Vakharia, BS Shepherd… - Viruses, 2020 - mdpi.com
Viral hemorrhagic septicemia virus (VHSV) is one of the most deadly infectious fish
pathogens, posing a serious threat to the aquaculture industry and freshwater ecosystems …

High virulence differences among phylogenetically distinct isolates of the fish rhabdovirus viral hemorrhagic septicaemia virus are not explained by variability of the …

K Einer-Jensen, A Harmache… - Journal of General …, 2014 - microbiologyresearch.org
Viral hemorrhagic septicaemia virus (VHSV) is an important viral pathogen in European
rainbow trout farming. Isolates from wild marine fish and freshwater trout farms show highly …

Genetically engineered viral hemorrhagic septicemia virus (VHSV) vaccines

MS Kim, KH Kim - Fish & Shellfish Immunology, 2019 - Elsevier
Viral hemorrhagic septicemia virus (VHSV) has been one of the major causes of mortality in
a wide range of freshwater and marine fishes worldwide. Although various types of vaccines …

The role of infectious hematopoietic necrosis virus (IHNV) proteins in the modulation of NF-κB pathway during IHNV infection

Y Wu, M Guo, X Hua, K Duan, G Lian, L Sun… - Fish & shellfish …, 2017 - Elsevier
Viral infections frequently lead to the activation of host innate immune signaling pathways
involved in the defense against invading pathogens. To ensure their survival, viruses have …

Effect of CRISPR/Cas9-mediated knockout of either Mx1 or ISG15 gene in EPC cells on resistance against VHSV infection

MS Kim, KH Kim - Fish & Shellfish Immunology, 2019 - Elsevier
Although the type I interferon-mediated increase of Mx1 and ISG15 gene expression in
Epithelioma papulosum cyprini (EPC) cells has been reported, the antiviral role of Mx1 and …

In vivo virulence of viral haemorrhagic septicaemia virus (VHSV) in rainbow trout Oncorhynchus mykiss correlates inversely with in vitro Mx gene expression

I Cano, B Collet, C Pereira, R Paley, R van Aerle… - Veterinary …, 2016 - Elsevier
The in vitro replication of viral haemorrhagic septicaemia virus (VHSV) isolates from each
VHSV genotype and the associated cellular host Mx gene expression were analysed. All the …

Effect of suboptimal temperature on the regulation of endogenous antigen presentation in a rainbow trout hypodermal fibroblast cell line

QH Abram, T Rodriguez-Ramos, NC Bols… - Developmental & …, 2019 - Elsevier
Rainbow trout (Oncorhynchus mykiss) face low environmental temperatures over winter
months and during extreme low temperature events. Suboptimal temperatures are known to …

Identification of an interferon-stimulated gene, isg15, involved in host immune defense against viral infections in gilthead seabream (Sparus aurata L.)

D Álvarez-Torres, V Gómez-Abellán, M Arizcun… - Fish & shellfish …, 2018 - Elsevier
Interferons (IFNs) play a key role in the innate immunity of vertebrates against viral infections
by inducing hundreds of IFN-stimulated genes (ISGs), such as isg15. Isg15 is an ubiquitin …