Generation of recombinant viruses lacking an essential gene for the production of infective
viral particles would be a way to produce safety-enhanced live viral vaccines. The …

Non-virion (NV) protein is essential for an efficient replication increasing the pathogenicity of
the Salmonid novirhabdovirus (formerly IHNV), Piscine novirhabdovirus (formerly VHSV) …

The basis of pathogenicity of viral haemorrhagic septicaemia virus (VHSV) was analysed in
the transcriptome of a rainbow trout cell line inoculated with pathogenic and non-pathogenic …

Viral vector-based vaccines are promising candidates that deliver antigens of interest into
hosts. Particularly, a single-cycle virus possesses the immunogenicity of a live virus vaccine …

Viral haemorrhagic septicaemia virus (VHSV) represents an important disease of finfish. To
explore the potential of shRNAs to combat this disease nucleotide sequences of either the …

Simple Summary Replication studies are frequently based on viral production, which
provides limited information to understand certain processes. Therefore, to discover which …

Our previous studies demonstrated that the nonstructural NV protein of infectious
hematopoietic necrosis virus (IHNV) was essential for efficient viral replication and …

Mx proteins are main effectors of the antiviral innate immune response mediated by type I
interferon (IFN I). Actually, diverse Mx proteins from fish proved highly active against fish …

Virus infection often causes large amounts of mortality during teleost larvae stage. Strong
induction of innate immunity to increase survival rates of teleost larvae has been less …

Viral hemorrhagic septicemia virus (VHSV) is the causative agent of viral hemorrhagic
septicemia in fish, a disease that affects a number of teleost fish species including olive …