Over the last years, there have been advances in the use of data-driven techniques to
improve the definition, early recognition, subtypes characterisation, prognostication and …

Sepsis is involved in~ 20% of annual global deaths. Despite decades of research, the
current management of sepsis remains supportive rather than curative. Clinical trials in …

The current pandemic of coronavirus disease 2019 (COVID-19) has affected> 160 million
individuals to date, and has caused millions of deaths worldwide, at least in part due to the …

Children admitted to hospital with an acute illness and concurrent severe malnutrition
[complicated severe malnutrition (CSM)] have a high risk of dying. The biological processes …

Viral sepsis has been proposed as an accurate term to describe all multisystemic
dysregulations and clinical findings in severe and critically ill COVID-19 patients. The …

Sepsis is a life-threatening condition caused by an exaggerated reaction of the body to an
infection, that leads to organ failure or even death. Since sepsis can kill a patient even in just …

Sepsis, defined as the dysregulated immune response to an infection leading to organ
dysfunction, is one of the leading causes of mortality around the globe. Despite the …

Mortality in acute infections is mostly associated with sepsis, defined as 'life-threatening
organ dysfunction caused by a dysregulated host response to infection'. It remains …

Infections are common and need minimal treatment; however, occasionally, due to
inappropriate immune response, they can develop into a life-threatening condition known as …

Owing to the development of intensive care units, many patients survive their initial insults
but progress to chronic critical illness (CCI). Patients with CCI are characterized by …