Oocyte quality is a key factor influencing IVF success. The oocyte and surrounding cumulus
cells, known collectively as the cumulus oocyte complex (COC), communicate bi …

A major challenge in ART is to select high-quality oocytes and embryos. The metabolism of
oocytes and embryos has long been linked to their viability, suggesting the potential utility of …

Cellular metabolism is a key regulator of energetics, cell growth, regeneration, and
homeostasis. Spatially mapping the heterogeneity of cellular metabolic activity is of great …

Background Oocyte components are maternally provided, solely determine oocyte quality,
and coordinately determine embryo quality with zygotic gene expression. During oocyte …

Embryo quality assessment by optical imaging is increasing in popularity. Among available
optical techniques, light sheet microscopy has emerged as a superior alternative to confocal …

Embryo quality is an important determinant of successful implantation and a resultant live
birth. Current clinical approaches for evaluating embryo quality rely on subjective …

The challenges posed by climate change and increasing world population are stimulating
renewed efforts for improving the sustainability of animal production. To meet such …

This paper reports a non-invasive and high sensitivity microsystem for three-dimensional
(3D) imaging of live biological samples. The microsystem's features are demonstrated here …

Neurodegenerative lysosomal storage disorders typically arise from homozygous autosomal
recessive mutations in genes encoding catabolic lysosomal proteins, while heterozygous …