[HTML][HTML] Modulatory roles of ATP and adenosine in cholinergic neuromuscular transmission

AU Ziganshin, AE Khairullin, CHV Hoyle… - International Journal of …, 2020 - mdpi.com
A review of the data on the modulatory action of adenosine 5'-triphosphate (ATP), the main
co-transmitter with acetylcholine, and adenosine, the final ATP metabolite in the synaptic …

[HTML][HTML] Purinergic tuning of the tripartite neuromuscular synapse

C Sousa-Soares, JB Noronha-Matos… - Molecular …, 2023 - Springer
The vertebrate neuromuscular junction (NMJ) is a specialised chemical synapse involved in
the transmission of bioelectric signals between a motor neuron and a skeletal muscle fiber …

[HTML][HTML] P2 receptor signaling in motor units in muscular dystrophy

AE Khairullin, SN Grishin, AU Ziganshin - International Journal of …, 2023 - mdpi.com
The purine signaling system is represented by purine and pyrimidine nucleotides and
nucleosides that exert their effects through the adenosine, P2X and P2Y receptor families. It …

Comparative transcriptome analysis of slow-twitch and fast-twitch muscles in Kazakh horses

J Wang, W Ren, Z Sun, Z Han, Y Zeng, J Meng, X Yao - Meat Science, 2024 - Elsevier
This study conducted a thorough analysis of the myofiber type composition in the extensor
digitorum longus muscle (EDL) and soleus muscle (SOL) of Kazakh horses, across different …

The thermal sensitivity of purinergic modulation of contractile activity of locomotor and respiratory muscles in mice

AE Khairullin, AY Teplov, SN Grishin, AM Farkhutdinov… - Biophysics, 2019 - Springer
We have previously demonstrated that hypothermia significantly modulates the effect of ATP
on the contractile activities of various types of rodent locomotor muscles. The aim of this …

The influence of hypothermia on purinergic synaptic modulation in the rat diaphragm

AE Khairullin, AU Ziganshin, SN Grishin - Biophysics, 2020 - Springer
The pre-and postsynaptic effects of ATP on thermal sensibility in the diaphragm of the rat
have been studied. It has been found that reduction in the bath temperatute from 37 to 22° С …

[HTML][HTML] Presynaptic Purinergic Modulation of the Rat Neuro-Muscular Transmission

AE Khairullin, SN Grishin, AU Ziganshin - Current Issues in Molecular …, 2023 - mdpi.com
ATP, being a well-known universal high-energy compound, plays an important role as a
signaling molecule and together with its metabolite adenosine they both attenuate the …

Effects of low‐dose metformin on pre‐frailty among middle‐aged and elderly pre‐diabetic people

CF Huang, MS Shiao, TY Mao - JCSM Rapid Communications, 2022 - Wiley Online Library
Background Pre‐frailty has been identified as a clinically silent mechanism pre‐disposing
people to frailty. The goal of this study is to investigate the impact of low‐dose metformin on …

The effect of acute unilateral denervation injury on purinergic signaling in the cholinergic synapse

AE Khairullin, DV Efimova, VA Markosyan, SN Grishin… - Biophysics, 2021 - Springer
Previously, we found a change in the efficiency of the modulatory action of ATP under the
influence of some non-physiological factors at neuromuscular synapses in rodents. This …

[HTML][HTML] Effects of ATP on time parameters of contractility of rats' slow and fast skeletal muscles in normal and hypothermic conditions

AE Khairullin, SN Grishin, AI Gabdrahmanov… - Muscles, 2023 - mdpi.com
We have previously shown that hypothermia leads to an increase in the synaptic modulating
effects of ATP but not of adenosine in several different animal skeletal muscles. In this paper …