The social environment and the epigenome
The genome is programmed by the epigenome. Two of the fundamental components of the
epigenome are chromatin structure and covalent modification of the DNA molecule itself by …
epigenome are chromatin structure and covalent modification of the DNA molecule itself by …
Eukaryotic DNA methylation as an evolutionary device
V Colot, JL Rossignol - Bioessays, 1999 - Wiley Online Library
DNA methylation is catalyzed by a family of conserved DNA methyltransferases and is
widespread among protists, plants, fungi and animals. It is however absent in some species …
widespread among protists, plants, fungi and animals. It is however absent in some species …
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
To gain insight into the function of DNA methylation at cis-regulatory regions and its impact
on gene expression, we measured methylation, RNA polymerase occupancy and histone …
on gene expression, we measured methylation, RNA polymerase occupancy and histone …
A mammalian protein with specific demethylase activity for mCpG DNA
SK Bhattacharya, S Ramchandani, N Cervoni, M Szyf - Nature, 1999 - nature.com
DNA-methylation patterns are important for regulating genome functions, and are
determined by the enzymatic processes of methylation and demethylation. The …
determined by the enzymatic processes of methylation and demethylation. The …
DNA methylation is a reversible biological signal
S Ramchandani, SK Bhattacharya… - Proceedings of the …, 1999 - National Acad Sciences
The pattern of DNA methylation plays an important role in regulating different genome
functions. To test the hypothesis that DNA methylation is a reversible biochemical process …
functions. To test the hypothesis that DNA methylation is a reversible biochemical process …
DNA methylation, chromatin inheritance, and cancer
Cancer is a process driven by the accumulation of abnormalities in gene function. While
many of these changes are genetic, epigenetically mediated changes in gene expression …
many of these changes are genetic, epigenetically mediated changes in gene expression …
Potential local regulatory functions of inhibins, activins and follistatin in the ovary
PG Knight, C Glister - Reproduction, 2001 - rep.bioscientifica.com
The changing pattern of granulosa cell expression of inhibin/activin subunits and follistatin
during follicle development and their differential regulation by extrinsic and intraovarian …
during follicle development and their differential regulation by extrinsic and intraovarian …
[HTML][HTML] Specific epigenetic alterations of IGF2-H19 locus in spermatozoa from infertile men
CC Boissonnas, HE Abdalaoui, V Haelewyn… - European Journal of …, 2010 - nature.com
DNA methylation marks, a key modification of imprinting, are erased in primordial germ cells
and sex specifically re-established during gametogenesis. Abnormal epigenetic …
and sex specifically re-established during gametogenesis. Abnormal epigenetic …
Gametic imprinting in mammals
DP Barlow - Science, 1995 - science.org
Embryonic development in mammals is distinct from that in other vertebrates because it
depends on a small number of imprinted genes that are specifically expressed from either …
depends on a small number of imprinted genes that are specifically expressed from either …
Diet and the epigenetic (re) programming of phenotypic differences in behavior
Phenotypic diversity is shaped by both genetic and epigenetic mechanisms that program
tissue specific patterns of gene expression. Cells, including neurons, undergo massive …
tissue specific patterns of gene expression. Cells, including neurons, undergo massive …