Diabetic vascular diseases: molecular mechanisms and therapeutic strategies

Y Li, Y Liu, S Liu, M Gao, W Wang, K Chen… - Signal transduction and …, 2023 - nature.com
Vascular complications of diabetes pose a severe threat to human health. Prevention and
treatment protocols based on a single vascular complication are no longer suitable for the …

Advanced glycation end products and diabetes mellitus: mechanisms and perspectives

M Khalid, G Petroianu, A Adem - Biomolecules, 2022 - mdpi.com
Persistent hyperglycemic state in type 2 diabetes mellitus leads to the initiation and
progression of non-enzymatic glycation reaction with proteins and lipids and nucleic acids …

IDF diabetes Atlas: Global estimates of undiagnosed diabetes in adults for 2021

K Ogurtsova, L Guariguata, NC Barengo… - Diabetes research and …, 2022 - Elsevier
Aims To provide up-to-date estimates of undiagnosed diabetes mellitus (UDM) prevalence-
both globally, and by region/country, for the year 2021. Methods Data sources reporting …

Environmental risk factors of type 2 diabetes—An exposome approach

JWJ Beulens, MGM Pinho, TC Abreu, NR den Braver… - Diabetologia, 2022 - Springer
Type 2 diabetes is one of the major chronic diseases accounting for a substantial proportion
of disease burden in Western countries. The majority of the burden of type 2 diabetes is …

[HTML][HTML] Pleotropic effects of polyphenols in cardiovascular system

T Behl, S Bungau, K Kumar, G Zengin, F Khan… - Biomedicine & …, 2020 - Elsevier
Numerous epidemiological and clinical studies demonstrate the beneficial effects of
naturally occurring, polyphenol supplementations, on cardiovascular system. The present …

Use of human umbilical vein endothelial cells (HUVEC) as a model to study cardiovascular disease: A review

DJ Medina-Leyte, M Domínguez-Pérez, I Mercado… - Applied Sciences, 2020 - mdpi.com
Cardiovascular disease (CVD) is the leading cause of death worldwide, and extensive
research has been performed to understand this disease better, using various experimental …

Peripheral neuropathy and all-cause and cardiovascular mortality in US adults: a prospective cohort study

CW Hicks, D Wang, K Matsushita… - Annals of internal …, 2021 - acpjournals.org
Background: Growing evidence indicates that peripheral neuropathy (PN) is common even
in the absence of diabetes. However, the clinical sequelae of PN have not been quantified in …

Inflammatory targets in diabetic nephropathy

J Donate-Correa, D Luis-Rodríguez… - Journal of Clinical …, 2020 - mdpi.com
One of the most frequent complications in patients with diabetes mellitus is diabetic
nephropathy (DN). At present, it constitutes the first cause of end stage renal disease, and …

Nanohybrid double network hydrogels based on a platinum nanozyme composite for antimicrobial and diabetic wound healing

Z Zhou, X Mei, K Hu, M Ma, Y Zhang - ACS applied materials & …, 2023 - ACS Publications
Along with hypoxia, severe bacterial infection, and abnormal pH, continuous inflammatory
response hinders diabetic wounds from healing. It leads to the accumulation of large …

AAA revisited: a comprehensive review of risk factors, management, and hallmarks of pathogenesis

V Kessler, J Klopf, W Eilenberg, C Neumayer… - Biomedicines, 2022 - mdpi.com
Despite declining incidence and mortality rates in many countries, the abdominal aortic
aneurysm (AAA) continues to represent a life-threatening cardiovascular condition with an …