Skin wound healing is an intractable problem that represents an urgent clinical need. To
solve this problem, a large number of studies have focused on the use of exosomes (EXOs) …

A large number of clinical trials have shown stem cell therapy to be a promising therapeutic
approach for the treatment of cardiovascular diseases. Since the first transplantation into …

Background Human adipose stem cells (ASCs) have emerged as a promising treatment
paradigm for skin wounds. Recent works demonstrate that the therapeutic effect of stem cells …

MicroRNA (miRNA) is a class of small noncoding RNA involved in physiological and
pathological processes via the regulation of gene expression. Naked miRNAs are unstable …

Adipose-derived mesenchymal stem/stromal cells (ASCs) are an adult stem cell population
able to self-renew and differentiate into numerous cell lineages. ASCs provide a promising …

Background M2 macrophages and exosomes from adipose-derived stem cells (ASCs) are
both reported to promote angiogenesis. However, the possible synergistic effects between …

Refractory skin defects such as pressure ulcers, diabetic ulcers, and vascular ulcers
represent a challenge for clinicians and researchers in many aspects. The treatment …

Wounds occur when skin integrity is broken and the skin is damaged. With progressive
changes in the disease spectrum, the acute wounds caused by mechanical trauma have …

Adipose tissue stem cells (ASCs), known as multipotent stem cells, are most commonly used
in the clinical applications in recent years. Adipose tissues (AT) have the advantage in the …

Background Diabetic limb ischemia is a clinical syndrome and refractory to therapy. Our
previous study demonstrated that adipose-derived stem cells (ADSCs) overexpressing …