Free radicals (FRs) are unstable molecules that cause reactive stress (RS), an imbalance
between reactive oxygen and nitrogen species in the body and its ability to neutralize them …

Skeletal muscle disorders are mostly genetic and include several rare diseases. With
disease progression, muscle fibrosis and adiposis occur, resulting in limited mobility. The …

Parkinson's disease (PD) is the second most common progressive age-related
neurodegenerative disorder. Paramount evidence shed light on the role of PI3K/AKT …

Diabetes mellitus (DM) is characterized by impaired glucose and insulin metabolism,
resulting in chronic hyperglycemia. Hyperglycemia-induced inflammation is linked to the …

Skin is susceptible to premature aging in response to ultraviolet (UV) radiation-induced
oxidative stress, which can ultimately result in aberrant aging or age-related disorders …

Maternal exercise during pregnancy has emerged as a potentially promising approach to
protect offspring from cardiovascular disease, including hypertension. Although endothelial …

The hypothalamus is an important regulator of autonomic and endocrine functions also
involved in aging regulation. The aging process in the hypothalamus is accompanied by …

Recent human and animal studies have delineated hypertension can develop in the earliest
stage of life. A lack or excess of particular nutrients in the maternal diet may impact the …

Periodontitis is a chronic inflammatory disease characterized by the progressive and
irreversible destruction of the periodontium. Its aetiopathogenesis lies in the constant …

Backgrounds Developed countries have a high mortality rate from atherosclerosis and are
frequently linked to inflammation and other blood lipid disorders. MicroRNA expression can …