Matching chelators to radiometals for radiopharmaceuticals

EW Price, C Orvig - Chemical Society Reviews, 2014 - pubs.rsc.org
Radiometals comprise many useful radioactive isotopes of various metallic elements. When
properly harnessed, these have valuable emission properties that can be used for …

Ruthenium metallopharmaceuticals

MJ Clarke - Coordination Chemistry Reviews, 2003 - Elsevier
The well-developed synthetic chemistry of ruthenium, particularly with ammine, amine and
imine ligands, provides for many approaches to innovative new metallopharmaceuticals …

Transferrin/transferrin receptor‐mediated drug delivery

H Li, ZM Qian - Medicinal research reviews, 2002 - Wiley Online Library
Since transferrin was discovered more than half a century ago, a considerable effort has
been made towards understanding tranferrin‐mediated iron uptake. However, it was not …

Multivalent ions and biomolecules: Attempting a comprehensive perspective

O Matsarskaia, F Roosen‐Runge… - ChemPhysChem, 2020 - Wiley Online Library
Ions are ubiquitous in nature. They play a key role for many biological processes on the
molecular scale, from molecular interactions, to mechanical properties, to folding, to self …

A comparative study of aluminum (III), gallium (III), indium (III), and thallium (III) binding to human serum transferrin

WR Harris, L Messori - Coordination Chemistry Reviews, 2002 - Elsevier
Group 13 cations exhibit an essentially similar chemical behavior in aqueous solution.
Under physiological conditions these cations exist as metal complexes. They are known to …

Reconsideration of serum Ti (IV) transport: albumin and transferrin trafficking of Ti (IV) and its complexes

AD Tinoco, EV Eames… - Journal of the American …, 2008 - ACS Publications
The trafficking of titanium (IV) by human serum transferrin (HsTf) has been implicated in the
physiology of this hydrolysis-prone metal. The current work broadens to include the further …

[HTML][HTML] Comparative analysis of rare earth elements concentrations in domestic dogs and Apennine wolves of Central Italy: influence of biological, nutritional, and …

M Bellocci, SVP Defourny, V Melai, G Scortichini… - Science of the Total …, 2024 - Elsevier
Abstract Rare Earth Elements (REEs) are strategical elements playing a crucial role in the
industry, especially in producing high-tech materials. Therefore, REEs are new …

Structural Consequences of Binding of UO22+ to Apotransferrin:  Can This Protein Account for Entry of Uranium into Human Cells?

C Vidaud, S Gourion-Arsiquaud, F Rollin-Genetet… - Biochemistry, 2007 - ACS Publications
It has been established that transferrin binds a variety of metals. These include toxic uranyl
ions which form rather stable uranyl-transferrin derivatives. We determined the extent to …

Understanding the in vivo fate of radioimmunoconjugates for nuclear imaging

D Vivier, SK Sharma, BM Zeglis - Journal of Labelled …, 2018 - Wiley Online Library
Over the past 25 years, antibodies have emerged as extraordinarily promising vectors for the
delivery of radionuclides to tumors for nuclear imaging. While radioimmunoconjugates often …

[图书][B] Metalloproteomics

E Permyakov - 2009 - books.google.com
Synthesizes the current knowledge in the field and provides new insights into medical
applications Metalloproteomics is the large-scale study of metal-binding proteins. These …