Immunotherapy in head and neck cancer: where do we stand?

NG Vallianou, A Evangelopoulos, D Kounatidis… - Current Oncology …, 2023 - Springer
Abstract Purposeof Review Head and neck cancer (HNC) comprises a group of
malignancies, amongst which squamous cell carcinoma accounts for more than 90% of the …

Targeting PI3K/AKT/mTOR signaling pathway as a radiosensitization in head and neck squamous cell carcinomas

YC Su, WC Lee, CC Wang, SA Yeh, WH Chen… - International Journal of …, 2022 - mdpi.com
Globally, there are over half a million new patients with head and neck squamous cell
carcinomas (HNSCC) every year. The current therapeutic approaches to HNSCC are …

Advantages of the combinatorial molecular targeted therapy of head and neck cancer—A step before anakoinosis-based personalized treatment

R Kleszcz - Cancers, 2023 - mdpi.com
Simple Summary Head and Neck Squamous Cell Carcinoma (HNSCC) is a major threat to
public health around the world. Its occurrence is linked to genetic events and environmental …

Prevalence of locoregional recurrence and survival post-treatment of head and neck cancers in Africa: a systematic review and meta-analysis

H Melariri, T Els, O Oyedele, TK Suttle… - …, 2023 - thelancet.com
Background Recurrent cancers of the head and neck are associated with poor survival
outcome. Yet, their burden in Africa is not reliably known. We therefore aimed to estimate the …

Whole exome sequencing uncovers HRAS mutations as potential mediators of resistance to metronomic chemotherapy

J Sambath, V Noronha, SS Manda, R Mishra… - Gene, 2024 - Elsevier
Objectives The aim of this pilot study is to identify the genetic factors that contribute to the
response of metronomic chemotherapy in head and neck squamous cell carcinoma …

Recent advances in head and neck surgical oncology

A Ritter, H Levyn, J Shah - Journal of Surgical Oncology, 2024 - Wiley Online Library
In recent years, the field of head and neck oncology has witnessed a remarkable
transformation with unprecedented advances that have revolutionized the management of …

[HTML][HTML] Molecular pathways and targeted therapies in head and neck cancers pathogenesis

M Constantin, MC Chifiriuc, C Bleotu… - Frontiers in …, 2024 - ncbi.nlm.nih.gov
The substantial heterogeneity exhibited by head and neck cancer (HNC), encompassing
diverse cellular origins, anatomical locations, and etiological contributors, combined with the …

[HTML][HTML] Molecular targeted therapies for cutaneous squamous cell carcinoma: recent developments and clinical implications

H Singh, H Chopra, I Singh, S Mohanto, MG Ahmed… - EXCLI …, 2024 - ncbi.nlm.nih.gov
Abstract Cutaneous Squamous Cell Carcinoma (cSCC) is a common and potentially fatal
type of skin cancer that poses a significant threat to public health and has a high prevalence …

Exploring the frontiers: tumor immune microenvironment and immunotherapy in head and neck squamous cell carcinoma

S Liu, R Wang, J Fang - Discover Oncology, 2024 - Springer
The global prevalence of head and neck malignancies positions them as the sixth most
common form of cancer, with the head and neck squamous cell carcinoma (HNSCC) …

Machine learning developed a macrophage signature for predicting prognosis, immune infiltration and immunotherapy features in head and neck squamous cell …

Y Wang, YK Mou, WC Liu, HR Wang, XY Song… - Scientific Reports, 2024 - nature.com
Macrophages played an important role in the progression and treatment of head and neck
squamous cell carcinoma (HNSCC). We employed weighted gene co-expression network …