Impact of retinoic acid on immune cells and inflammatory diseases

LM Oliveira, FME Teixeira… - Mediators of inflammation, 2018 - Wiley Online Library
Vitamin A metabolite retinoic acid (RA) plays important roles in cell growth, differentiation,
organogenesis, and reproduction and a key role in mucosal immune responses. RA …

Retinoic acid and retinoic acid receptors as pleiotropic modulators of the immune system

A Larange, H Cheroutre - Annual review of immunology, 2016 - annualreviews.org
Vitamin A is a multifunctional vitamin implicated in a wide range of biological processes. Its
control over the immune system and functions are perhaps the most pleiotropic not only for …

Vitamin A plasma levels in COVID-19 patients: a prospective multicenter study and hypothesis

PR Tepasse, R Vollenberg, M Fobker, I Kabar… - Nutrients, 2021 - mdpi.com
COVID-19 is a pandemic disease that causes severe pulmonary damage and
hyperinflammation. Vitamin A is a crucial factor in the development of immune functions and …

[HTML][HTML] Vitamin A and retinoic acid in T cell–related immunity

AC Ross - The American journal of clinical nutrition, 2012 - Elsevier
Interest in vitamin A as a regulator of immune function goes back to the early 1900s.
Recently, several lines of evidence have converged to show that retinoic acid (RA), a major …

Role of retinoic acid in the imprinting of gut-homing IgA-secreting cells

JR Mora, UH von Andrian - Seminars in immunology, 2009 - Elsevier
Antibody-secreting cells (ASCs) lodging in the mucosa of the small intestine are derived
from activated B cells that are thought to arise in gut-associated lymphoid tissues (GALT) …

Mega doses of retinol: A possible immunomodulation in Covid‐19 illness in resource‐limited settings

IK Midha, N Kumar, A Kumar… - Reviews in medical …, 2021 - Wiley Online Library
Of all the nutrients, vitamin A has been the most extensively evaluated for its impact on
immunity. There are three main forms of vitamin A, retinol, retinal and retinoic acid (RA) with …

Vitamin A and retinoic acid in the regulation of B-cell development and antibody production

AC Ross, Q Chen, Y Ma - Vitamins & Hormones, 2011 - Elsevier
Signaling by vitamin A through its active metabolite retinoic acid (RA) is critical for the
normal development and functions of the hematopoietic and immune systems. B cells, as …

Innate mechanisms in selective IgA deficiency

J Zhang, D van Oostrom, JX Li… - Frontiers in …, 2021 - frontiersin.org
Selective IgA deficiency (SIgAD), characterized by a serum IgA level below 0.07 mg/ml,
while displaying normal serum levels of IgM and IgG antibodies, is the most frequently …

Microbiota metabolite short-chain fatty acids facilitate mucosal adjuvant activity of cholera toxin through GPR43

W Yang, Y Xiao, X Huang, F Chen, M Sun… - The Journal of …, 2019 - journals.aai.org
The gut microbiota has been shown critical for mucosal adjuvant activity of cholera toxin
(CT), a potent mucosal adjuvant. However, the mechanisms involved remain largely …

[HTML][HTML] In ovo co-administration of vitamins (A and D) and probiotic lactobacilli modulates immune responses in broiler chickens

M Alizadeh, J Astill, N Alqazlan, B Shojadoost… - Poultry science, 2022 - Elsevier
There is evidence that probiotic lactobacilli, in addition to essential vitamins, such as vitamin
A and D, have immunomodulatory properties that enhance immune response of neonatal …