[HTML][HTML] Understanding the Molecular Actions of Spike Glycoprotein in SARS-CoV-2 and Issues of a Novel Therapeutic Strategy for the COVID-19 Vaccine

Y Matsuzaka, R Yashiro - BioMedInformatics, 2024 - mdpi.com
In vaccine development, many use the spike protein (S protein), which has multiple “spike-
like” structures protruding from the spherical structure of the coronavirus, as an antigen …

Comprehensive proteomic analysis of HCoV-OC43 virions and virus-modulated extracellular vesicles

N Joharinia, É Bonneil, N Grandvaux… - Journal of …, 2024 - Am Soc Microbiol
Viruses are obligate parasites that depend on the cellular machinery for their propagation.
Several viruses also incorporate cellular proteins that facilitate viral spread. Defining these …

Multiple pro-viral effects of the host protein G3BP in SARS-CoV-2 Infection

G McInerney, S Long, LP Vidakovics, X Han, R Sun… - 2024 - researchsquare.com
Ras-GTPase-activating protein SH3-domain-binding proteins (G3BP) are multifunctional
RNA-binding proteins, pivotal in the initiation of stress granules (SGs). SARS-CoV-2 …