[HTML][HTML] Integrating basic science with translational research: the 13th International Podocyte Conference 2021

F Lausecker, S Koehler, M Fresquet, RW Naylor… - Kidney International, 2022 - Elsevier
The 13th International Podocyte Conference was held in Manchester, UK, and online from
July 28 to 30, 2021. Originally planned for 2020, this biannual meeting was postponed by a …

[HTML][HTML] The adaptor protein Grb2 is not essential for the establishment of the glomerular filtration barrier

N Bisson, J Ruston, M Jeansson, R Vanderlaan… - PLoS …, 2012 - journals.plos.org
The kidney filtration barrier is formed by the combination of endothelial cells, basement
membrane and epithelial cells called podocytes. These specialized actin-rich cells form long …

Novel role of Vav1-Rac1 pathway in actin cytoskeleton regulation in interleukin-13-induced minimal change-like nephropathy

CY Chan, KH Ng, J Chen, J Lu, CGL Lee… - Clinical …, 2016 - portlandpress.com
Our established interleukin-13 (IL-13) overexpression rat model of minimal change-like
nephropathy provided a platform to study the molecular signalling pathways in T-helper 2 …

Sex Differences in Glomerular Protein Expression and Effects of Soy-Based Diet on Podocyte Signaling

A Mahesaniya, CR Williamson… - … Journal of Kidney …, 2022 - journals.sagepub.com
Background: Kidney disease is a major public health issue arising from loss of glomerular
podocyte function, and there are considerable sex differences in its prognosis. Evidence …

Prospects for precision medicine in glomerulonephritis treatment

YC Liu, J Chun - Canadian Journal of Kidney Health and …, 2018 - journals.sagepub.com
Background: Glomerulonephritis (GN) consists of a group of kidney diseases that are
categorized based on shared histopathological features. The current classifications for GN …

Formation and maintenance of a functional glomerulus

RP Scott, SE Quaggin - Kidney Development, Disease, Repair and …, 2016 - Elsevier
The renal glomerulus is an elegant structure that serves as an exquisitely selective plasma
filtration unit. The glomerulus has been conserved throughout evolution and has a basic …

足细胞骨架相关蛋白的调节及其在细胞生物学中的作用

陶花, 顾乐怡 - 中国中西医结合肾病杂志, 2011 - cqvip.com
肾小球血管上皮细胞, 也称足细胞, 是一种特殊终末分化细胞. 足细胞可分为: 细胞体, 初级突起,
足突. 微管和中间丝构成足细胞体和初级突起的支架. 微丝则是足突的细胞骨架 …

The podocyte cytoskeleton: key to a functioning glomerulus in health and disease

C Faul - Podocytopathy, 2014 - karger.com
Background: Proteinuria is a cardinal sign of chronic kidney disease, which is a major
healthcare problem that affects millions of people worldwide. Recent advances in molecular …

血管紧张素Ⅱ 对足细胞nephrin 磷酸化水平的影响

任志龙, 梁伟, 丁国华, 陈铖, 周敏, 徐婉, 杨红霞 - 中华肾脏病杂志, 2012 - cqvip.com
目的通过建立血管紧张素Ⅱ (AngⅡ) 输注大鼠模型及体外足细胞培养, 观察AngⅡ
刺激对足细胞nephrin 磷酸化水平的影响. 方法30 只SPF 级Wistar 大鼠皮下埋置渗透性微泵 …

A broad clinical spectrum of PLCε1-related kidney disease and intrafamilial variability

EK Yılmaz, S Saygili, B Gulhan, N Canpolat… - Pediatric …, 2022 - Springer
Background The phenotypic and genotypic spectrum and kidney outcome of PLCε1-related
kidney disease are not well known. We attempted to study 25 genetically confirmed cases of …